头颈部肿瘤放射性甲状腺功能减退的研究现状  

Research progress inradiation-induced hypothyroidism in patients with head and neck cancers

作　　者：王婵 侯彦杰[1] 杨烨 李险峰[1] Wang Chan;Hou Yanjie;Yang Ye;Li Xianfeng(Department of Radiation Oncology,the First Hospital of Shanxi Medical University,Taiyuan 030000,China)

机构地区：[1]山西医科大学第一医院放疗科,太原030000

出　　处：《中华放射医学与防护杂志》2021年第11期867-873,共7页Chinese Journal of Radiological Medicine and Protection

摘　　要：放疗是头颈部肿瘤重要的治疗手段,由于解剖结构复杂,放疗时甲状腺难免会受到照射,照射造成的放射性甲状腺功能减退(RIHT,radiation-induced hypothyroidism,放射性甲减)及其对身体机能的影响逐渐引起人们关注。本文就头颈部肿瘤RIHT的临床特点、发生机制、危险因素、预测模型、评估及治疗等进行综述。Radiotherapy is an important treatment method for head and neck cancers.However,owing to the complex anatomic structure,the thyroid will be inevitably radiated during radiotherapy.Radiation-induced hypothyroidism(RIHT)and its impacts on somatic function have gradually attracted people′s attention.This review summarizes the clinical characteristics,pathogenesis,risk factors,predictive models,assessment,and treatment of RIHT of patients with head and neck cancers.

关 键 词：头颈部肿瘤 放射治疗 甲状腺损伤 放射性甲状腺功能减退 

分 类 号：R739.91[医药卫生—肿瘤] R581.2[医药卫生—临床医学]