Application of dental stem cells in three-dimensional tissue regeneration  

作　　者：Hui-Yi Hsiao Chung-Yi Nien Hsiang-Hsi Hong Ming-Huei Cheng Tzung-Hai Yen 

机构地区：[1]Center for Tissue Engineering,Chang Gung Memorial Hospital,Linkou Branch,Taoyuan 333,Taiwan [2]Department of Life Sciences,National Central University,Zhongli,Taoyuan 320,Taiwan [3]Department of Periodontics,Chang Gung Memorial Hospital,Linkou Branch,Taoyuan 333,Taiwan [4]Division of Reconstructive Microsurgery,Department of Plastic and Reconstructive Surgery,Chang Gung Memorial Hospital,Linkou Branch,College of Medicine,Chang Gung University,Taoyuan 333,Taiwan [5]Department of Nephrology,Clinical Poison Center,Chang Gung Memorial Hospital,Linkou Branch,Taoyuan 333,Taiwan [6]School of Traditional Chinese Medicine,College of Medicine,Chang Gung University,Taoyuan 333,Taiwan

出　　处：《World Journal of Stem Cells》2021年第11期1610-1624,共15页世界干细胞杂志（英文版）（电子版）

基　　金：Supported by Chang Gung Memorial Hospital,Linkou,Taiwan,No.CORPG3K0021 and No.CORPG3K0191.

摘　　要：Dental stem cells can differentiate into different types of cells.Dental pulp stem cells,stem cells from human exfoliated deciduous teeth,periodontal ligament stem cells,stem cells from apical papilla,and dental follicle progenitor cells are five different types of dental stem cells that have been identified during different stages of tooth development.The availability of dental stem cells from discarded or removed teeth makes them promising candidates for tissue engineering.In recent years,three-dimensional(3D)tissue scaffolds have been used to reconstruct and restore different anatomical defects.With rapid advances in 3D tissue engineering,dental stem cells have been used in the regeneration of 3D engineered tissue.This review presents an overview of different types of dental stem cells used in 3D tissue regeneration,which are currently the most common type of stem cells used to treat human tissue conditions.

关 键 词：Dental stem cells Dental pulp stem cells Stem cells from human exfoliated deciduous teeth Periodontal ligament stem cells Stem cells from apical papilla Dental follicle progenitor cells Three-dimensional tissue regeneration 

分 类 号：R781[医药卫生—口腔医学]