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作 者:闫晓旭 焦卓敏[1] YAN Xiao-xu;JIAO Zhuo-min(The Second Affiliated Hospital of Harbin Medical University,Harbin 150000,China)
机构地区:[1]哈尔滨医科大学附属第二医院,哈尔滨150000
出 处:《中国临床神经科学》2021年第6期713-717,共5页Chinese Journal of Clinical Neurosciences
摘 要:高级前庭功能疾病(HVeD)是指涉及多种感觉及认知领域(如,方向、空间记忆和导航)障碍的前庭功能紊乱性疾病,包括房间倾斜错觉、单侧空间忽视、Pusher综合征以及伴空间记忆缺失的双侧前庭疾病。目前对HVeD的相关研究较少,其病因、发病机制及病理生理尚未明确,单一的神经损伤或系统功能障碍不能完全解释此疾病的发生发展过程。且HVeD临床表现缺乏特异性,增加了漏诊率,也为后续治疗及疗效评估带来很大的困扰。文中旨在通过收集国内外关于HVeD的研究现状,对其病因、发病机制、治疗及预后进行介绍。Higher vestibular function disorder(HVeD)is a disease that involves disorders in various sensory and cognitive domains,such as orientation,spatial memory and navigation.It includes room tilt illusion,unilateral spatial neglect,Pusher syndrome and bilateral vestibulopathy with spatial amnesia.At present,there are few studies on the etiology,pathogenesis and pathophysiology of HVeD.And a single neurological injury or systemic dysfunction cannot fully explain the occurrence and development of this disease.The lack of specificity in clinical manifestations of HVeD increases the rate of missed diagnosis,and brings great difficulties for the subsequent treatment and evaluation of efficacy.The current research of HVeD in etiology,pathogenesis,treatment and prognosis were reviewed.
关 键 词:高级前庭功能疾病 房间倾斜错觉 单侧空间忽视 PUSHER综合征 双侧前庭病
分 类 号:R745.1[医药卫生—神经病学与精神病学] R764.3[医药卫生—临床医学]
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