山药及麸炒山药拉曼指纹图谱分析  

Analysis of Raman fingerprint spectra for Dioscoreae Rhizoma and Dioscoreae Rhizoma stir-fried with bran

作　　者：彭艳[1] 张丽颖[1] 金阳[1] 杨钊 陆兔林[3] 金传山 都述虎[1] PENG Yan;ZHANG Li-ying;JIN Yang;YANG Zhao;LU Tu-lin;JIN Chuan-shan;DU Shu-hu(School of Pharmacy,Nanjing Medical University,Nanjing 211166,China;Joinative Traditional Chinese Medicine Industry Co.,Ltd.,Wuhan 430040,China;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China;School of Pharmacy,Anhui University of Chinese Medicine,Hefei 230012,China)

机构地区：[1]南京医科大学药学院,江苏南京211166 [2]九州天润中药产业有限公司,湖北武汉430040 [3]南京中医药大学药学院,江苏南京210046 [4]安徽中医药大学药学院,安徽合肥230012

出　　处：《中成药》2021年第12期3403-3408,共6页Chinese Traditional Patent Medicine

基　　金：国家重点研发计划资助(2018YFC1707000)。

摘　　要：目的比较山药片与麸炒山药饮片的拉曼指纹图谱差异。方法采用拉曼光谱技术,分别建立山药对照药材、不同产地的山药片和麸炒山药饮片拉曼指纹图谱,确定山药特征拉曼光谱谱峰位置及归属。结果山药的拉曼光谱显示出了可溶性淀粉的拉曼指纹特征,判别分析可以有效区分广西山药和其他产地山药。山药麸炒后,478 cm^(-1)处的特征峰强度显著降低,并在468 cm^(-1)处和491 cm^(-1)处出现2个新的拉曼峰。结论山药麸炒前后拉曼指纹图谱有明显差异,表明麸炒后的山药主成分(淀粉)有所变化,所建立的分析方法为完善山药饮片及麸炒山药饮片的质量评价体系奠定了基础。AIM To compare Raman fingerprint spectra between Dioscoreae Rhizoma(Chinese yam)and Dioscoreae Rhizoma stir-fried with bran.METHODS Raman spectroscopic technique was used to acquire the Raman fingerprint spectra of Chinese yam for control use,common Chinese yam from different areas and Chinese yam stir-fried with bran,and the Raman characteristic peaks of Chinese yam and their assignments,respectively.RESULTS Chinese yam displayed identical Raman spectrum with the soluble starch.Discriminant analysis effectively distinguished Chinese yam of Guangxi from other producing areas.Stir-frying with bran brought forth significant decrease in characteristic peak intensity of Chinese yam at 478 cm^(-1),but appearance of two new Raman peaks at 468 cm^(-1)and 491 cm^(-1).CONCLUSION The significant differences in the Raman fingerprint spectra of Chinese yam before and after stir-frying with bran suggest the change in its composition(starch).The proposed method for the Raman analysis of Chinese yam highlights the further quality control of common Chinese yam and Chinese yam stir-fried with bran.

关 键 词：拉曼光谱 山药 麸炒山药 淀粉 质量控制 

分 类 号：R282.5[医药卫生—中药学]