^(1)H-NMR技术在中药分析领域的应用现状  

Application status of ^(1)H-NMR technology in analysis of traditional Chinese medicine

作　　者：徐博 吴翠[1,2] 李卓俊 宋平平 巢志茂 XU Bo;WU Cui;LI Zhuo-jun;SONG Ping-ping;CHAO Zhi-mao(Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Storage&Packaging Position,Chinese Materia Medica,China Agriculture Research System,Beijing 100700,China)

机构地区：[1]中国中医科学院中药研究所,北京100700 [2]国家中药材产业技术体系贮藏与包装岗位,北京100700

出　　处：《药物分析杂志》2021年第10期1663-1669,共7页Chinese Journal of Pharmaceutical Analysis

基　　金：财政部和农业农村部:国家现代农业产业技术体系资助(CARS-21)。

摘　　要：氢核磁共振(^(1)H-NMR)是解析化合物结构的有力工具,定性、定量的分析方法已在生物、医疗卫生、食品、石油化工、地质及化学材料等领域发挥着重要的作用。本文从研究方法和应用现状等方面对^(1)H-NMR技术进行了综述,分析了其在应用中的局限性,并结合中药研究的特点和需求对未来的发展趋势进行展望,以期为该技术更好地用于中药分析研究提供参考。Proton nuclear magnetic resonance(^(1)H-NMR)is a powerful tool for identifying compound structure and a common method for qualitative and quantitative study.It has played an important role in several fields such as biology,health care,food,petrochemical industry,geology,and chemical materials.In this paper,current research methods and the latest application status of ^(1)H-NMR technology were reviewed for the first time.The limitations of this technology were also discussed.Meanwhile,the paper prospected the future development trend according to characteristics and requirement of traditional Chinese medicine in order to offer reference for better study.

关 键 词：氢核磁共振 中药分析 应用现状 机制研究 代谢组学 结构解析 指纹图谱 

分 类 号：R917[医药卫生—药物分析学]