化学计量学在中药色谱分析中的应用探讨  

Discussion on the application of chemometrics in chromatographic analysis of traditional Chinese medicine

作　　者：熊婧[1] 李慧勇 李广生 石岩[1] 何兰[1] 魏锋[1] 马双成[1] XIONG Jing;LI Hui-yong;LI Guang-sheng;SHI Yan;HE Lan;WEI Feng;MA Shuang-cheng(National Institutes for Food and Drug Control,Beijing 102629,China;Heilongjiang Institute for Drug Control,Haerbin 150088,China)

机构地区：[1]中国食品药品检定研究院,北京102629 [2]黑龙江省药品检验研究中心,哈尔滨150088

出　　处：《药物分析杂志》2021年第10期1681-1689,共9页Chinese Journal of Pharmaceutical Analysis

摘　　要：化学计量学是一门涵盖多学科的交叉学科,对于中药色谱分析产生的海量数据具有极大的分析和处理优势,可促进中药色谱分析的进步。本文从中药分析中常用的色谱技术出发,对化学计量学在分析实验的设计、色谱数据的处理、有效数据信息的提取、色谱数据的分析等各过程中的应用分别进行了论述,为化学计量学在中药分析中的进一步应用提供参考。Chemometrics is an interdisciplinary subject covering many disciplines,which has great advantages in analyzing and processing the massive data generated by chromatographic analysis of traditional Chinese medicine(TCM). It can promote the progress of chromatographic analysis of TCM. Starting from the chromatographic techniques commonly used in the analysis of TCM,this paper discusses the application of chemometrics in the design of analytical experiment,the processing of chromatographic data,the extraction of effective data information and the analysis of chromatographic data,in order to provide reference for the further application of chemometrics in the analysis of TCM.

关 键 词：中药 质量分析 色谱 化学计量学 主成分分析法 偏最小二乘法 

分 类 号：R917[医药卫生—药物分析学]