清胃散加减辅助治疗儿童急性牙髓炎胃火炽盛证44例临床观察  

Clinical observation on 44 cases of acute pulpitis in children with intense stomach-fire syndrome treated by modified Qingwei San(清胃散)as adjuvant therapy

作　　者：巫遂燕 林仁[2] 邹媚 樊彤海[2] WU Suiyan;LIN Ren;ZOU Mei;FAN Tonghai(School of Postgraduate,Zhejiang Chinese Medical University,Hangzhou,Zhejiang,310053,China;Department of Stomatology,Lishui The People’s Hospital,Lishui,Zhejiang,323200,China)

机构地区：[1]浙江中医药大学研究生院,浙江杭州310053 [2]丽水市人民医院口腔科,浙江丽水323200

出　　处：《中医儿科杂志》2021年第6期70-73,共4页Journal of Pediatrics of Traditional Chinese Medicine

摘　　要：目的观察清胃散加减辅助治疗儿童急性牙髓炎胃火炽盛证的临床疗效。方法选取2019年2月至2020年2月丽水市人民医院口腔科收治的急性牙髓炎胃火炽盛证患儿86例,采用随机数字表法分为治疗组44例和对照组42例。对照组给予常规西药治疗,治疗组在对照组治疗方法的基础上给予清胃散加减治疗,2组均治疗7 d后统计疗效。结果对照组总有效率为71.43%(30/42),治疗组为93.18%(41/44),2组比较,差异有统计学意义(P<0.05)。治疗前2组视觉疼痛模拟评分法(VAS)评分比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组VAS评分均明显降低,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。对照组咀嚼功能恢复正常时间为(6.12±0.56)d,治疗组为(5.07±0.49)d,2组比较,差异有统计学意义(P<0.05)。治疗前2组血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)及C-反应蛋白(CRP)水平比较,差异无统计学意义(P>0.05),具有可比性。治疗后2组TNF-α、IL-6、IL-1β及CRP水平均明显降低,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。结论清胃散加减辅助治疗儿童急性牙髓炎胃火炽盛证疗效显著,能明显缓解患儿疼痛感,加快咀嚼功能恢复时间,抑制炎症因子递质的表达,值得临床推广应用。Objective To observe the clinical efficacy of modified Qingwei San(清胃散)in adjuvant treatment of acute pulpitis in children with intense stomach-fire syndrome.Methods From February 2019 to February 2020,86 cases of acute pulpitis in children with intense stomach-fire syndrome admitted into department of stomatology in Lishui The People’s Hospital were divided into treatment group with 44 cases and control group with 42 cases according to random number table method.The control group was given routine Western medicine treatment,on this basis,the treatment group was given modified Qingwei San,and we kept statistics about the efficacy after the 2 groups were both treated for 7 days.Results The total effective rate of the control group was 71.43%(30/42),that of the treatment group was 93.18(41/44),and the difference was statistically significant between the 2 groups(P<0.05).Before treatment,the difference was not statistically significant in visual analogue scale(VAS)score between the 2 groups(P>0.05),indicating comparability.After treatment,VAS scores of the 2 groups both significantly decreased,and the difference was statistically significant compared with those of the same group before treatment(P<0.05),moreover,the treatment group decreased more significantly(P<0.05).The recovery time of returning to normal of masticatory function in the control group was(6.12±0.56)days,and that in the treatment group was(5.07±0.49)days,and the difference was statistically significant between the 2 groups(P<0.05).Before treatment,the difference was not statistically significant in serum levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),interleukin-1β(IL-1β)and C-reactive protein(CRP)between the 2 groups(P>0.05),indicating comparability.After treatment,the levels of TNF-α,IL-6,IL-1βand CRP in the 2 groups all significantly decreased compared with those of the same group before treatment,and the difference was statistically significant(P<0.05),moreover,the treatment group decreased more significantly(P<0.05

关 键 词：儿童 急性牙髓炎 胃火炽盛证 清胃散 临床观察 

分 类 号：R781.31[医药卫生—口腔医学]