非小细胞肺癌立体定向放疗所致放射性肺炎相关因素研究进展  

Research progress on risk factors of radiation pneumonitis caused by stereotactic body radiotherapy for non-small-cell lung cancer

作　　者：付守鹏 张英杰 李建彬 Fu Shoupeng;Zhang Yingjie;Li Jianbin(Weifang Medical University,Weifang 261053,China;Department of Radiation Oncology,Shandong Cancer Hospital and Institute,Shandong First Medical University and Shandong Academy of Medical Sciences,Ji′nan 250117,China)

机构地区：[1]潍坊医学院,261053 [2]山东省肿瘤防治研究院(山东省肿瘤医院),山东第一医科大学(山东省医学科学院)放疗科,济南250117

出　　处：《中华放射肿瘤学杂志》2021年第12期1330-1334,共5页Chinese Journal of Radiation Oncology

基　　金：国家自然基金青年基金项目(81201735);山东省重点研发计划项目(2015 GSF118011)。

摘　　要：立体定向放疗现已成为早期非小细胞肺癌治疗的重要选择。放射性肺炎是早期非小细胞肺癌患者立体定向放疗后主要不良反应。患者因素、肿瘤因素、治疗因素等都与早期非小细胞肺癌患者立体定向放疗后放射性肺炎的发生相关。近年来的相关研究进一步明确了这些因素与放射性肺炎的关联,而且对与RP发生相关的预测因素进行了进一步探讨。本文对近年来的相关研究结果进行了综述。Stereotactic body radiotherapy(SBRT/SABR)has become an important option in the treatment of early non-small-cell lung cancer(NSCLC).Radiation pneumonitis(RP)is the main side effect of early NSCLC patients after SBRT/SABR.Patient factors,tumor factors and treatment factors are all associated with the occurrence of RP in early NSCLC patients after SBRT/SABR.In recent years,relevant studies have further clarified the relationship between these factors and RP.In addition,the prediction factors related to RP occurrence are further discussed.In this paper,relevant research progresses in recent years were reviewed.

关 键 词：放射性肺炎 危险因素 癌 非小细胞肺/立体定向放射疗法 

分 类 号：R734.2[医药卫生—肿瘤]