^(99m)Tc-MIBI显像与剪切波弹性成像对甲状腺癌诊断价值的对比研究  

Comparative Value of ^(99m)Tc-MIBI Imaging and Shear Wave Elastography in the Diagnosis of Thyroid Carcinoma

作　　者：陶绪长[1] 王豪 蔡风 陈庆杰[2] 颜金花[1] TAO Xuzhang;WANG Hao;CAI Feng(The First Hospital of Nanchang,Nanchang,330006)

机构地区：[1]南昌市第一医院,330006 [2]南昌大学第一附属医院,330008

出　　处：《实用癌症杂志》2021年第12期1964-1966,共3页The Practical Journal of Cancer

基　　金：江西省教育厅科学技术研究项目(编号:GJJ200208)。

摘　　要：目的探讨^(99m)Tc-MIBI显像与剪切波弹性成像对甲状腺癌诊断的应用价值差异。方法将超声检查证实为单发非囊性结节,甲状腺^(99m)TcO_(4)^(-)显像提示为单发“冷”或“凉”结节的65例患者纳入研究。按随机数字表法将患者随机分为3组,A组(超声剪切波弹性成像组,n=22),B组(核素^(99m)Tc-MIBI亲肿瘤显像组,n=22),C组(超声剪切波弹性成像+核素^(99m)Tc-MIBI亲肿瘤显像组,n=21)。以术后病理为确诊依据,分析比较3种检查方法对甲状腺癌的诊断准确率、敏感性、特异性、阳性预测值及阴性预测值。结果与单独应用超声剪切波弹性成像和^(99m)Tc-MIBI显像诊断相比,二者联合诊断的灵敏度、准确率最高,差异有统计学意义(P<0.05)。结论在甲状腺癌诊断中,联合应用剪切波弹性成像与^(99m)Tc-MIBI显像有利于评估病灶性质,提高诊断准确性,其应用价值较高,值得推广使用。Objective To investigate the difference of ^(99m)Tc-MIBI imaging and shear wave elastography in the diagnosis of thyroid carcinoma.Methods 65patients whose ultrasound examination confirmed to be single non-cystic nodules with thyroid ^(99m)TcO_(4)^(-)imaging suggesting single"cold"or"cool"nodules because of the discovery of neck clumps were selected as object of study.The patients were divided into 3 groups according to the random number table,group A(shear wave elastography group,n=22),group B(^(99m)Tc-MIBI thyroid imaging group,n=22),group C(shear wave elastography+^(99m)Tc-MIBI thyroid imaging group,n=21).On the basis of postoperative pathological results,the accuracy,sensitivity,specificity,positive predictive value and negative predictive value for the diagnosis of thyroid carcinoma among the 3 groups were compared.Results The sensitivity and the accuracy of shear wave elastography combined with ^(99m)Tc-MIBI thyroid imaging were higher than single shear wave elastography or ^(99m)Tc-MIBI thyroid imaging,and the difference was statistically significant(P<0.05).Conclusion The application of shear wave elastography combined with ^(99m)Tc-MIBI imaging on the diagnosis of thyroid carcinoma can evaluate the nature of the lesion,and improve the diagnostic accuracy,which has high application value and is worthy of popularization and application.

关 键 词：甲状腺癌 ^(99m)Tc-MIBI显像 剪切波弹性成像 应用价值 

分 类 号：R736.1[医药卫生—肿瘤]