基于大脑皮质细胞构筑的癫痫脑定位学  

Brain mapping for epilepsy based on cytoarchitectonics

作　　者：张玮[1] 冯硕[2] 陈倩[2] 刘兴洲 Zhang Wei;Feng Shuo;Chen Qian;Liu Xingzhou(Department of Neurology,Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University,Beijing 102218,China;Department of Neurology,Children's Hospital Capital Institute of Pediatrics,Beijing 100020,China)

机构地区：[1]清华大学附属北京清华长庚医院神经内科,北京102218 [2]首都儿科研究所附属儿童医院神经内科,北京100020

出　　处：《中国医学前沿杂志（电子版）》2021年第12期34-41,共8页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

摘　　要：现代癫痫病学实践证明,局灶性癫痫发作症状学分析可为致痫区定位诊断提供关键线索。立体定向脑电图学派遵循的“解剖-电-临床关联”原则将立体定向脑电图工作原理建立在“网络动态学”理念基础之上。大脑皮质纤维联系和信息处理遵循由皮质构筑属性决定的等级架构原则,这一原则同样可应用到“解剖-电-临床关联”的工作原理中,指导不同皮质起源癫痫发作的定位诊断。Chronological semiological sequence has been proven to provide key cue for mapping epileptogenic zone based on current clinical practice of epileptology.The principle of"anatomo-electro-clinical correlation"bases stereoelectroen-cephalography(SEEG)practice on neuro-network dynamics.The connectivity and information processing in the cerebral cortex is hierarchical,which principle is appropriately matched in the mapping of epileptogenic zone for focal epilepsy guided on theory of"anatomoelectro-clinical correlation".

关 键 词：局灶性癫痫 立体定向脑电图 解剖-电-临床关联 细胞构筑 

分 类 号：R742.1[医药卫生—神经病学与精神病学]