重型甲型血友病致下肢假瘤伴迁延不愈感染性皮肤溃疡一例  

A case of pseudotumor of lower extremity combined with protracted infectious skin ulcer induced by severe hemophilia A

作　　者：陈斓 谢卫国 余刚 Chen Lan;Xie Weiguo;Yu Gang(Department of Burns,Tongren Hospital of Wuhan University&Wuhan Third Hospital,Wuhan 430060,China)

机构地区：[1]武汉大学同仁医院暨武汉市第三医院烧伤科,430060

出　　处：《中华烧伤杂志》2021年第12期1191-1193,共3页Chinese Journal of Burns

摘　　要：2018年7月11日武汉大学同仁医院暨武汉市第三医院收治1例因重型甲型血友病致下肢假瘤伴迁延不愈感染性皮肤溃疡26岁男性患者。经行补充凝血因子、凝血酶原复合物及清创、负压封闭引流等治疗,患者创面形成肉芽组织后行皮片移植。术后行凝血因子补充及抗感染、预防血肿等治疗,最终皮片存活、创面封闭,患者生活质量得到明显改善。该病例提示积极有效的手术治疗可以明显改善重型甲型血友病患者预后。On July 11,2018,a 26 years old male patient with pseudotumor of lower extremity combined with protracted infectious skin ulcer induced by severe hemophilia A was admitted to Tongren Hospital of Wuhan University&Wuhan Third Hospital.After treatment of supplementary of clotting factors,prothrombin complex,debridement,and vacuum sealing drainage,skin grafting was performed after granulation tissue formation in wounds.After surgery,clotting factor supplement,anti-infection,prevention of hematoma,and so on were performed.The wounds were finally closed with the survival of skin graft,which dramatically improves the patient's quality of life.This case suggests that aggressive and effective surgical treatment can significantly improve the prognosis of patients with severe hemophilia A.

关 键 词：血友病A 皮肤溃疡 伤口愈合 

分 类 号：R845.2+2[医药卫生—航空、航天与航海医学] Q2[医药卫生—临床医学]