社会认知与交互训练对早发性精神分裂症患者社会认知功能的影响  

Effects of the social cognition and interaction training on the social cognitive function in patients with early onset schizophrenia patients

作　　者：江小英[1] 赵勇 唐文新 JIANG Xiao-ying;ZHAO Yong;TANG Wen-xing(Affiliated Mental Health Center&Hangzhou Seventh People's Hospital,Zhejiang University School of Medicine,Hangzhou 310013,China)

机构地区：[1]浙江大学医学院附属精神卫生中心,杭州市第七人民医院,310013

出　　处：《临床精神医学杂志》2021年第6期453-455,共3页Journal of Clinical Psychiatry

基　　金：杭州市科技局(20191203B120)。

摘　　要：目的:探索社会认知与交互训练(SCIT)对早发性精神分裂症患者社会认知功能的影响。方法:将70例经单一非典型抗精神病药治疗后病情稳定的早发性精神分裂症患者随机分为干预组及对照组各35例;两组在原药物治疗的基础上,干预组接受规范的SCIT共4周;分别于干预前后采用人际感知任务量表(IPT-15)及社交回避及苦恼量表(SAD)评估患者的社交能力,采用心理推理能力故事图片任务(TOM-PST)及失言识别任务评估患者的心理理论能力。结果:干预后,干预组IPT-15中的亲属关系、从属关系、欺骗关系3项因子分明显高于干预前,且亲属关系、欺骗关系两项因子分明显高于对照组(P均<0.01);SAD评分明显低于干预前(P<0.01)及对照组(P<0.05);TOM-PST总分及等级错误信念评分明显提高,且明显高于对照组(P<0.05或P<0.01);失言情景理解评分明显提高(P<0.01),并明显高于对照组(P<0.05);对照组干预前后各项评分比较差异无统计学意义。结论:SCIT可辅助病情稳定的早发性精神分裂症患者改善社会认知功能。Objective:To explore the characteristics of the social cognition and interaction training(SCIT)on the social cognitive function in patients with early onset schizophrenia(EOS)patients.Method:Seventy EOS patients were treated with single atypical antipsychotic drugs in stable period,they were randomly divided into intervention group(n=35)and control group(n=35).Both groups were treated with the original drug,SCIT group received SCIT intervention for 4 weeks.All patients were assessed with the social ability with interpersonal perception task-15(IPT-15),social avoidance and distress scale(SAD),theory of mind ability with Picture-sequencing Task(TOM-PST)and Faux pas recognition before and after treatment.Results:After SCIT intervention,the kinship,affiliation and deception subscores of IPT-15 in the intervention group were significantly higher than those before intervention,and the scores of kinship and deception were significantly higher than those in the control group(P<0.01).The SAD score in the intervention group was significantly lower than that before intervention(all P<0.01)and control group(P<0.05).Moreover,total score and grade false belief error score in the Tom-PST were significantly higher than those of control group(P<0.05 or P<0.01).The score of episodic comprehension significantly increased after SCIT intervention(P<0.01),and significantly higher than those of the control group(P<0.05).There was no significant difference in the above scores of the control group before and after intervention.Conclusion:SCIT may improve the ability of the social cognition in stable phase of EOS as an adjunctive therapy.

关 键 词：早发性精神分裂症 社会认知与交互训练 社会认知功能 

分 类 号：R749.3[医药卫生—神经病学与精神病学]