中枢神经系统感染性疾病的脑脊液宏基因组学第二代测序应用专家共识  

Expert consensus on clinical application of metagenomic next-generation sequencing of cerebrospinal fluid in the diagnosis of infectious diseases of the central nervous system

作　　者：中华医学会神经病学分会感染性疾病与脑脊液细胞学学组 赵钢 王佳伟[3] 关鸿志[4] Chinese Society of Infectious Diseases and Cerebrospinal Fluid Cytology;Zhao Gang;Wang Jiawei;Guan Hongzhi(不详;Northwest University School of Medicine,Xi'an 710069,China;Department of Neurology,Beijing Tongren Hospital Affiliated to Capital Medical University,Beijing 100730,China;Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]不详 [2]西北大学医学院,西安710069 [3]首都医科大学附属北京同仁医院神经内科100730 [4]中国医学科学院北京协和医院神经科100730

出　　处：《中华神经科杂志》2021年第12期1234-1240,共7页Chinese Journal of Neurology

摘　　要：宏基因组学第二代测序能够非靶向地检测临床标本中的病原体核酸,在中枢神经系统感染性疾病的病原体诊断方面,已逐步应用于临床。为推进脑脊液宏基因组学第二代测序的合理应用,中华医学会神经病学分会感染性疾病与脑脊液细胞学学组基于国内外研究成果与专家经验,组织撰写了该共识。Metagenomic next-generation sequencing(mNGS),a new technique for pathogen identification,is increasingly used for the clinical diagnosis of infectious diseases of the central nervous system.Based on the previous studies and expert opinions,the Chinese Society of Infectious Diseases and Cerebrospinal Fluid Cytology developed this consensus to standardize the clinical application of mNGS of cerebrospinal fluid.

关 键 词：脑炎 脑膜炎 诊断 脑脊液 宏基因组学第二代测序 

分 类 号：R742.9[医药卫生—神经病学与精神病学]