《世界卫生组织基本药物标准清单》2021版与2019版收录药品变化  

Essential drug changes between the 2021 and 2019 editions of World Health Organization Model List of Essential Medicines

作　　者：赵飞 赵紫楠[2] 金鹏飞[2] 李可欣[1] 薛薇[1] 齐文渊[1] 王娟 徐晓宇 刘晓慧 杨蕾 丛端端 张亚同[2] 胡欣[2] ZHAO Fei;ZHAO Zi-nan;JIN Peng-fei;LI Ke-xin;XUE Wei;QI Wen-yuan;WANG Juan;XU Xiao-yu;LIU Xiao-hui;YANG Lei;CONG Duan-duan;ZHANG Ya-tong;HU Xin(Clinical Trial Center,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China;Department of Pharmacy,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京医院临床试验研究中心,国家老年医学中心,中国医学科学院老年医学研究院,北京100730 [2]北京医院药学部国家老年医学中心,中国医学科学院老年医学研究院,北京100730

出　　处：《临床药物治疗杂志》2021年第11期69-72,共4页Clinical Medication Journal

基　　金：北京市科技计划课题(Z191100007619038);中国药学会-施维雅青年医院药学创新研究资助项目(001)。

摘　　要：目的研究2021年9月30日世界卫生组织出版的2021版《世界卫生组织基本药物标准清单》(以下简称《标准清单》)更新情况,为我国基本药物遴选提供参考。方法将2021版与2019版《标准清单》进行比对,分析删减和新增药品特点。结果2021版《标准清单》共列出479种药品,较2019版的459种删减4种、新增24种药品。2021版《标准清单》新增加了牙科制剂大类,纳入更多抗感染药物和抗肿瘤药物、精准治疗的药物、固定剂量复方制剂、吸入药物、长效胰岛素类似物。结论纳入"新药"一直是《标准清单》更新的趋势,并且2021年版《标准清单》提示精准治疗药物、联合治疗药物和长效疗程药物是未来药物开发的重点方向之一。Objective To study the update of 2021 edition of World Health Organization Model List of Essential Medicines(hereinafter referred to as "Model List")published by World Health Organization on September 30,2021,to provide reference for the selection of essential medicines in China. Methods We compared the 2021 edition of the Model List with the2019 edition of the Model List,and analyzed the characteristics of the deleted and newly added drugs. Results The 2021 edition of the Model List had a total of 479 medicines,with 4 deletions and 24 new medicines compared to 459 in the 2019 edition. The 2021 edition of the Model List added a new major category of dental preparations,and incorporated more anti-infective and anti-tumor drugs. Drugs for precision therapy,fixed-dose combinations,more inhalation drugs and long-acting insulin analogues were included. Conclusion The inclusion of "new drugs" has been the trend of updating the Model List,and the new version of the Model List suggested that precision therapy drugs,combination therapy drugs and long-acting course drugs are one of the key directions for future drug development.

关 键 词：世界卫生组织基本药物标准清单 基本药物 世界卫生组织 

分 类 号：R95[医药卫生—药学]