^(99)Tc^(m)-MDP全身骨显像联合SPECT/CT诊断骨外肿瘤  

^(99)Tc^(m)-MDP whole-body bone imaging combined with SPECT/CT for diagnosis of extraosseous tumors

作　　者：张林启 黄培莉 何巧[2] 李淑仪 张静 马立武 彭浩 张汝森 ZHANG Linqi;HUANG Peili;HE Qiao;LI Shuyi;ZHANG Jing;MA Liwu;PENG Hao;ZHANG Rusen(Department of Nuclear Medicine,Affiliated Cancer Hospital and Institute of Guangzhou Medical University,Guangzhou 510095,China;Department of Nuclear Medicine,the First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510055,China)

机构地区：[1]广州医科大学附属肿瘤医院核医学科,广东广州510095 [2]中山大学附属第一医院核医学科,广东广州510055

出　　处：《中国医学影像技术》2021年第12期1870-1873,共4页Chinese Journal of Medical Imaging Technology

基　　金：广州市卫生健康科技项目(20201A011102)。

摘　　要：目的观察^(99)Tc^(m)-亚甲基二磷酸盐(MDP)全身骨显像联合SPECT/CT诊断骨外肿瘤的价值。方法回顾性分析68例骨外肿瘤患者94处病灶,观察其全身骨显像及SPECT/CT表现,并分析二者联合诊断效能。结果单纯全身骨显像准确诊断52处骨外肿瘤,准确率55.32%(52/94);其余42处病灶中,35处(35/94,37.23%)因影像学表现与骨骼存在重叠而误诊为转移性骨肿瘤,7处(7/94,7.45%)因病灶^(99)Tc^(m)-MDP摄取低于邻近骨骼而致漏诊。全身骨显像联合SPECT/CT诊断全部94处骨外肿瘤,准确率100%(94/94)。94处病灶中,49处接受病理学检查,其中33处(33/49,67.35%)病灶内见粗大钙化、9处(9/49,18.37%)见细微钙化;CT检出61处(61/94,64.89%)钙化,未显示9处细微钙化。结论^(99)Tc^(m)-MDP全身骨显像联合SPECT/CT可提高诊断骨外肿瘤的准确性。Objective To observe the value of^(99)Tc^(m)-labelled methylene diphosphonate(^(99)Tc^(m)-MDP)whole-body bone imaging combining with SPECT/CT for diagnosis of extraosseous tumors.Methods A total of 94 lesions in 68 patients with extraosseous tumors were enrolled.The whole-body bone imaging and SPECT/CT manifestations of lesions were retrospectively analyzed,and the combining diagnostic efficacy was analyzed.Results The accuracy of whole-body bone imaging for diagnosis of extraosseous tumors was 55.32%(52/94).Among the rest 42 lesions,35(35/94,37.23%)were misdiagnosed as metastatic bone tumors due to overlapping imaging findings with bones,while 7(7/94,7.45%)were misdiagnosed due to lower uptake of^(99)Tc^(m)-MDP than adjacent bones.The accuracy of whole-body bone imaging combining with SPECT/CT for diagnosis of extraosseous tumors was 100%(94/94).Pathological examination of 49 lesions were performed,among which coarse calcifications were detected in 33 lesions(33/49,67.35%)and fine calcifications in 9(9/49,18.37%)lesions.CT showed intratumoral calcifications in 61 lesions(61/94,64.89%),not including the above 9 fine calcifications.Conclusion^(99)Tc^(m)-MDP whole body bone imaging combining with SPECT/CT could improve the accuracy of diagnosing extraosseous tumors.

关 键 词：肿瘤 99M锝美罗酸盐 放射性核素显像 正电子发射断层显像 体层摄影术 X线计算机 

分 类 号：R73[医药卫生—肿瘤] R817.4[医药卫生—临床医学]