“分子”心理治疗:基因在心理治疗中的作用  

Molecular Psychotherapy:The Role of Genes in Psychotherapy

作　　者：王慧泽 袁勇贵[1,2] WANG Huize;YUAN Yonggui(School of Medicine,Southeast University,Nanjing 210009,China;Zhongda Hospital,Southeast University,Nanjing 210009,China)

机构地区：[1]东南大学医学院,南京210009 [2]东南大学附属中大医院心理精神科,南京210009

出　　处：《心理学通讯》2021年第3期168-173,共6页Psychological Communications

摘　　要：精神疾病受多种因素影响,与遗传变异和环境暴露均有关。关于遗传-环境相互作用的大多数研究集中于遗传变异与压力以及创伤性事件共同对心理健康的长期影响。越来越多的研究发现,遗传变异对于心理治疗的结局也有一定影响。通过讨论遗传变异对心理治疗的影响,以期帮助临床医生为患者选择最佳的治疗方案。Mental illness is influenced by multiple factors and is associated with genetic variation and environmental exposure.Most researches on gene-environment interactions have focused on the joint effect of genetic variation and stress in addition to traumatic experiences on the long-term impact on mental health,but a growing number of studies have found that genetic variants also play a role in treatment outcomes.The impact of genetic variation on psychotherapy is discussed in the hope of helping clinicians choose the best treatment for patients.

关 键 词：心理治疗 5-羟色胺转运蛋白基因关联多态性区域 单胺氧化酶A 儿茶酚-O-甲基转移酶 脑源性神经营养因子 

分 类 号：R749.055[医药卫生—神经病学与精神病学]