Study on the Correlation between Syndrome Differentiation of Malignant Pleural Effusion Treated by External Treatment of Traditional Chinese Medicine and Immunohistochemistry of Biopsy Tissue Based on Medical Video-assisted Thoracoscope  

作　　者：De-Min Li Xin-Yang Shu Dao-Wen Yang Bing-Lin Zhang Zhen Wang 

机构地区：[1]Department of Pulmonary Diseases of Traditional Chinese Medicine,Center of Respiratory Medicine,China-Japan Friendship Hospital,Beijing,China,National Center for Respiratory Medicine,Beijing,China,Institute of Respiratory Medicine,Chinese Academy of Medical Sciences,Beijing,China,Beijing 100029 National Clinical Research Center for Respiratory Diseases,Beijing,China [2]Department of Pathology,China-Japan Friendship Hospital,Beijing 100029,China [3]Beijing Institute of Respiratory Diseases,Department of Respiratory and Critical Care Medicine,Beijing Chaoyang Hospital Affiliated to Capital Medical University,Beijing 100020,China.

出　　处：《Cancer Advances》2021年第6期19-22,共4页TMR肿瘤进展

摘　　要：Objective:Guided by the theory of syndrome differentiation of yin and yang in traditional Chinese medicine surgery,through visual observation of internal medicine thoracoscope,comprehensive observation of pleural cavity and immunohistochemistry of biopsy tissue,to classify malignant pleural effusion according to syndrome differentiation,and to explore the scientific nature of its theory.Methods:From March 1,2014 to February 28,2015,40 cases of malignant pleural effusion were treated in Beijing Chaoyang Hospital affiliated to Capital Medical University.According to the proposed TCM diagnostic criteria for yin and yang syndrome differentiation,and collect age,gender,course of disease,clinical symptoms,tumor primary focus,histomorphological manifestations and immunohistochemical results and other related information,and carry out statistical data processing.Results:The positive syndrome was mainly metastatic lung adenocarcinoma,which accounted for the majority of all MPE cases,up to 75%.The immunohistochemical results of biopsy tissues were mainly CEA and TTF-1 positive;While pleural effusion caused by pleural mesothelioma was the main type of yin syndrome,and the results of immunohistochemistry combined with biopsy were mainly positive for D2-40,Calretinin,WT-1 and CK5/6.Conclusion:TCM syndrome differentiation of MPE based on internal thoracoscopy combined with biopsy immunohistochemical results has sufficient theoretical basis and certain scientific nature,and further clinical research is needed to verify its effectiveness and practicability in the future.

关 键 词：malignant pleural effusion medical thoracoscope external treatment of traditional Chinese medicine syndrome differentiation IMMUNOHISTOCHEMISTRY 

分 类 号：R73[医药卫生—肿瘤]