失眠与微觉醒的相关研究进展  

Research Progress on Insomnia and Microarousal

作　　者：王茹 唐吉友[1] WANG Ru;TANG Jiyou(Department of Neurology,Shandong Qianfoshan Hospital,Cheeloo College of Medicine,Shandong University,Jinan 250014,China)

机构地区：[1]山东大学附属山东省千佛山医院神经内科,济南250014

出　　处：《中国医学科学院学报》2021年第6期945-949,共5页Acta Academiae Medicinae Sinicae

基　　金：国家自然科学基金(81471345)。

摘　　要：失眠症是以入睡和/或睡眠维持困难所致的睡眠质量或数量达不到正常生理需求而影响日间社会功能的一种主观体验,对人体各个系统均有慢性损害,是最常见的睡眠障碍性疾患。失眠症发生和维持的主要机制是过度觉醒假说,微觉醒作为皮质觉醒,也参与过度觉醒机制的形成。本文对微觉醒的机制及临床意义进行了梳理和总结,以期对临床工作有指导意义。Insomnia is a subjective experience of difficulty in falling asleep and/or maintaining sleep accompanied by the impairment of daytime social functioning due to insufficient sleep quality or quantity to meet normal physiological needs.It has chronic damage to all the human body systems and is the most common sleep disorder.The main mechanism for the occurrence and maintenance of insomnia is the hyperarousal hypothesis,and microarousal,as a cortical arousal,is also involved in the formation of the hyperarousal mechanism.The mechanism and clinical significance of microarousal were reviewed and summarized in this paper in order to guide the clinical work.

关 键 词：微觉醒 觉醒 失眠 过度觉醒 睡眠碎片化 记忆 抑郁 

分 类 号：R741[医药卫生—神经病学与精神病学]