双水相体系在酶催化药物合成中的研究进展  

Recent Advance of Enzymatic Pharmaceutical Synthesis in Aqueous Two-Phasic Systems

作　　者：林锦良 陈小芳 李友凤 Lin Jinliang;Chen Xiaofang;Li Youfeng(Department of Chemistry and Chemical Engineering,Zunyi Normal College,Zunyi,Guizhou 563002,China)

机构地区：[1]遵义师范学院化学化工学院,贵州遵义563002

出　　处：《绿色科技》2021年第24期214-217,共4页Journal of Green Science and Technology

基　　金：贵州省科技项目(编号:黔科合基础-ZK[2021]058);贵州省教育项目(编号:黔教合KY字[2018]311&[2019]105)。

摘　　要：双水相体系在抗生素类、神经类、维生素类和凝胶微球等药物及其辅剂的酶催化合成中具有广泛的应用。通过对上述类型反应进行归纳分析,结果证明了双水相体系中酶催化合成作为一种新型的药物合成途径,具有高效、易分离和可循环利用等优点。对此进行相关综述,可为促进相关研究领域的发展提供参考。Aqueous two phasic systems(ATPS)have been widely used in enzymatic pharmaceutical synthesis,which includes antibiotics,neuro kinds,vitamins and relievers.In this paper,the above-mentioned types of reactions are summarized and analyzed.The results from these reactions illustrated that ATPS is a novel approach with high efficiency,easily separation and recycled utilization.Hence,this review gives referential significance on the relevant research fields.

关 键 词：双水相体系 酶催化 药物合成 循环利用 

分 类 号：O643[理学—物理化学]