有机氟化物的电化学合成  

Electrosynthesis of Organic Fluorides

作　　者：张子杭 李思哲 阚立言 温俊 卞江[1] Zihang Zhang;Sizhe Li;Liyan Kan;Jun Wen;Jiang Bian(College of Chemistry and Molecular Engineering,Peking University,Beijing 100871,China)

机构地区：[1]北京大学化学与分子工程学院,北京100871

出　　处：《大学化学》2021年第12期193-213,共21页University Chemistry

摘　　要：有机氟化物在很多领域(尤其是药物方面)有着广泛的应用,但鉴于氟的特殊反应性,氟原子的引入一直是有机化学中的难题。而有机电化学合成作为近年来新兴的合成手段,大大拓宽了有机反应的界限,使得更多绿色简易的氟化方法被开发了出来。本文就将集中列举这些有机电化学方法氟化的实例,并探讨电化学方法对于氟化学这一领域可能的推动作用。Organic fluorides have been widely applied in various spheres,especially in the medical field.However,due to the distinctive reactivity of fluorine,the introduction of fluorine atom has always been a problem in organic chemistry.As a novel synthetic method developed in recent years,organic electrochemical synthesis has greatly expanded the boundaries of organic reactions,which have enabled the development of many efficient and eco-friendly fluorination methods.In this paper,we will focus on these examples of electro-chemical fluorination,and discuss the possible role of electrochemical methods in the field of fluoro-chemistry.

关 键 词：有机电化学 氟化学 有机合成 方法学 

分 类 号：G64[文化科学—高等教育学] O6[文化科学—教育学]