DSA三维重建技术引导射频消融治疗肺恶性肿瘤的临床应用  

Clinical application of radiofrequency ablation guided by threedimensional digital subtraction angiography in the treatment of pulmonary malignancy

作　　者：刘辉来[1] 文自祥[1] LIU Huilai;WEN Zixiang(Department of Interventional Medicine,the People's Hospital of Zhongshan City,Guangdong,Zhongshan 528400,China)

机构地区：[1]广东省中山市人民医院介入医学科,广东中山528400

出　　处：《中国医药科学》2021年第23期162-164,240,共4页China Medicine And Pharmacy

基　　金：广东省中山市卫生健康局医学科研项目(2021J049)。

摘　　要：目的分析数字减影血管造影(DSA)三维重建技术引导射频消融治疗肺恶性肿瘤的临床应用。方法选取2019年1月至2021年4月中山市人民医院介入医学科收治的肺恶性肿瘤患者96例,根据治疗方法不同分为对照组和研究组,各48例,对照组实施CT引导下的射频消融术进行治疗,研究组实施DSA三维重建技术引导射频消融进行治疗,观察两组患者临床指标、生活质量水平及术后并发症发生情况。结果研究组患者在血清癌胚抗原(CEA)、白细胞计数(WBC)、血小板计数(PLT)、白介素-6(IL-6)以及肿瘤坏死因子(TNF)等临床指标情况明显高于对照组,差异有统计学意义(P<0.05);研究组患者干预后生活质量水平显著高于对照组,差异有统计学意义(P<0.05);研究组患者胸腔积液、气胸、肺部感染以及心包积液等术后并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。结论对肺恶性肿瘤患者实施DSA三维重建技术引导射频消融进行治疗,可很好地改善患者临床各项生理指标,提高患者生活质量水平,降低患者术后并发症发生率,促进患者快速康复。Objective To analyze the clinical application of radiofrequency ablation guided by threedimensional digital subtraction angiography(3D-DSA)in the treatment of pulmonary malignancy.Methods A total of 96 patients with pulmonary malignancy admitted to the Department of Interventional Medicine of the People's Hospital of Zhongshan City from January 2019 to April 2021 were selected as research objects.They were divided into the control group and the study group according to different treatment methods,with 48 cases in each group.The control group was treated with CT-guided radiofrequency ablation,while the study group was treated with 3D-DSA-guided radiofrequency ablation.Clinical indicators,quality of life and postoperative complications of the two groups were observed.Results The levels of carcinoembryonic antigen(CEA),white cell count(WBC),platelet count(PLT),interleukin-6(IL-6)and tumor necrosis factor(TNF)in the study group were significantly higher than those in the control group,with statistically significant differences(P<0.05).After intervention,the quality of life in the study group was significantly higher than that in the control group,with statistically significant difference(P<0.05).The incidence of postoperative complications such as pleural effusion,pneumothorax,pulmonary infection and pericardial effusion in the study group was significantly lower than that in the control group,with statistically significant difference(P<0.05).Conclusion 3D-DSA-guided radiofrequency ablation can improve the clinical physiological indexes of patients,improve their quality of life,reduce the incidence of postoperative complications and promote their rapid recovery.

关 键 词：肺恶性肿瘤 DSA三维重建 射频消融术 并发症 生活质量 

分 类 号：R734.2[医药卫生—肿瘤] R730.55[医药卫生—临床医学]