Autism spectrum disorder and personality disorders: Comorbidity and differential diagnosis  

作　　者：Camilla Rinaldi Margherita Attanasio Marco Valenti Monica Mazza Roberto Keller 

机构地区：[1]Adult Autism Center,Department of Mental Health,ASL Cittàdi Torino,Turin 10138,Italy [2]Department of Applied Clinical Sciences and Biotechnology,University of L’Aquila,L’Aquila 67100,Italy [3]Regional Centre for Autism,Abruzzo Region Health System,L’Aquila 67100,Italy

出　　处：《World Journal of Psychiatry》2021年第12期1366-1386,共21页世界精神病学杂志

摘　　要：BACKGROUND Differential diagnosis,comorbidities and overlaps with other psychiatric disorders are common among adults with autism spectrum disorder(ASD),but clinical assessments often omit screening for personality disorders(PD),which are especially common in individuals with high-functioning ASD where there is less need for support.AIM To summarize the research findings on PD in adults with ASD and without intellectual disability,focusing on comorbidity and differential diagnosis.METHODS PubMed searches were performed using the key words“Asperger’s Syndrome”,“Autism”,“Personality”,“Personality disorder”and“comorbidity”in order to identify relevant articles published in English.Grey literature was identified through searching Google Scholar.The literature reviews and reference sections of selected papers were also examined for additional potential studies.The search was restricted to studies published up to April 2020.This review is based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method.RESULTS The search found 22 studies carried out on ASD adults without intellectual disability that met the inclusion criteria:16 evaluated personality profiles or PD in ASD(comorbidity),five compared ASD and PD(differential diagnosis)and one performed both tasks.There were significant differences in the methodological Cluster A and cluster C PD are the most frequent co-occurring PD,but overlapping features should be considered.Data on differential diagnosis were only found with cluster A and cluster B PD.CONCLUSION ASD in high-functioning adults is associated with a distinct personality profile even if variability exists.Further studies are needed to explore the complex relationship between ASD and PD.

关 键 词：Autism spectrum disorder Asperger’s Syndrome Personality disorder ADULTHOOD COMORBIDITY Differential diagnosis 

分 类 号：R749.94[医药卫生—神经病学与精神病学] R749.91[医药卫生—临床医学]