Magnetic challenge against gastroesophageal reflux  

作　　者：Mauro Bortolotti 

机构地区：[1]Via Massarenti 48,Bologna 40138,Italy

出　　处：《World Journal of Gastroenterology》2021年第48期8227-8241,共15页世界胃肠病学杂志（英文版）

摘　　要：Almost 15 years have passed since the first paper on the possibility of using magnets to prevent gastro-esophageal reflux(GER)was published and so it is time to assess the results obtained with the first magnetic device available on the market,the Linx magnetic sphincter augmentation(MSA)and to consider what other options are forthcoming.MSA demonstrated an anti-reflux activity similar to that of Nissen fundoplication,considered the“gold standard”surgical treatment for GER disease,and caused less gas-bloating and a better ability to allow vomiting and belching.However,unlike Nissen fundoplication,this magnetic device is burdened by complications,which are roughly similar to those of the non-magnetic anti-reflux Angelchik prosthesis,that,after considerable use in the eighties,was shelved due to these complications.It is interesting to note that some of these complications show the same pathophysiological mechanism in both devices.The upcoming new magnetic devices should avoid these complications,as their anti-reflux magnetic mechanism is completely different.The experiments in animals regarding these new magnetic appliances were examined,remarking their advantages and drawbacks,but the way to apply them in surgical practice is long and difficult,although worthy,as they represent the future of magnetic surgery.

关 键 词：Gastro-esophageal reflux disease Magnetic sphincter augmentation device Nissen fundoplication Angelchik prosthesis Lower esophageal sphincter DYSPHAGIA 

分 类 号：R57[医药卫生—消化系统]