肌少症与炎症的研究进展  

Sarcopenia and Inflammation

作　　者：陈发秀[1] 梅洵[1] 唐月红[1] 付小红[1] 胡坚[1] CHEN Faxiu;MEI Xun;TANG Yuehong;FU Xiaohong;HU Jian(Departments of Geriatric Department, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang 330006)

机构地区：[1]江西省人民医院老年医学科,330006

出　　处：《中国老年保健医学》2021年第6期92-95,共4页Chinese Journal of Geriatric Care

基　　金：江西省卫健委科技计划项目(项目号202110001)。

摘　　要：肌少症是一种增龄性的老年综合征,以全身性肌肉力量、质量下降和机体功能减退为主要表现,与临床不良结局相关。肌少症发病机制复杂,包括与衰老相关的合成代谢激素、运动神经元缺失、肌卫星细胞凋亡、炎症通路、线粒体功能障碍等。炎症是肌少症的一个重要病理生理过程,笔者就肌少症与炎症的关系进行简要综述。Sarcopenia,the age-dependent decline of muscle mass and performance,is a common condition among elderly population and is related to numerous adverse health outcomes.Causes of sarcopenia are generally attributable to the natural processes of aging,which are not entirely understood and are multifaceted.Inflammation is considered as a major pathological causes of human sarcopenia.This review describes the effect of inflammation in skeletal muscle tissue function and possible mechanisms sarcopenia.

关 键 词：肌少症 炎症 促炎细胞因子 信号通路 

分 类 号：R73[医药卫生—肿瘤]