Long-term Di-(2-ethylhexyl) phthalate Exposure Disturbs the Lipid Metabolism Profiles and Hepatic Enzymes in Male Rats:A UPLC-MS-based Serum Metabolomics Analysis  

作　　者：DONG Xin Wen WU Wei Dong YAO San Qiao ZHANG Yun Bo WANG Cheng WU Hao Yu NA Xiao Lin 

机构地区：[1]Department of Environmental and Occupational Health,School of Public Health,Xinxiang Medical University,Xinxiang 453003,Henan,China [2]Department of Environmental Hygiene,Public Health College,Harbin Medical University,Harbin 150086,Heilongjiang,China

出　　处：《Biomedical and Environmental Sciences》2021年第11期920-925,共6页生物医学与环境科学（英文版）

基　　金：supported by the National Natural Science Foundation of China[Grant No.U2004102];the Natural Science Foundation of Henan Province[Grant No.202300410312];conducted in the laboratory of the Key Laboratory of Nutrition and Food Hygiene(Harbin Medical University);Heilongjiang Higher Education Institutions。

摘　　要：In recent years,many investigations have indicated that environmental endocrine disruptors(EEDs)may accelerate the development of obesity[1].One kind of EEDs,di-(2-ethylhexyl)phthalate(DEHP),is ubiquitous in natural environments due to its role in the manufacture and use of plastic products[2].

关 键 词：LIPID Metab SERUM 

分 类 号：R114[医药卫生—卫生毒理学]