Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones  

作　　者：Braulio Omar Manzo Jose David Cabrera Esteban Emiliani Hector Manuel Sanchez Brian Howard Eisner Jose Ernesto Torres 

机构地区：[1]Urology Department,Hospital Regional de Alta Especialidad del Bajio,Blvd.Milenio#130,Col.San Carlos la Roncha,Leon,Guanajuato,Mexico [2]Urology Department,Fundacion Puigvert,Universidad Autonoma de Barcelona,Barcelona,Spain [3]Urology Department,Massachusetts General Hospital,Harvard Medical School,Boston,USA

出　　处：《Asian Journal of Urology》2021年第3期275-279,共5页亚洲泌尿外科杂志（英文）

摘　　要：Objective:To assess the effect of the adherence to medical treatment on urinary parameters in the 24-h metabolic study of patients with kidney stones.Methods:A retrospective,longitudinal,descriptive,and observational study was carried out by reviewing the hospital electronic medical record from 2014 to 2018.The adherence to drug treatment was measured 6 months after its initiation,and the numerical values of the metabolic studies were compared.Wilcoxon tests were performed to compare the difference before and after treatment.Results:Ninety patients were evaluated,with 73.3% of adherence.The 180-day overall adherence rate was 61.2% in patients treated with a single drug and 85.4% in patients treated with multiple drugs.There is a statistically significant increase in citrate levels in patients with good adherence in comparison with non-adherent patients(p=0.031 vs.p=0.528).Conclusions:Medical treatment and dietary measures in patients with kidney stones have an initial impact at 6 months on the values of the main urinary metabolic alterations that predispose to calculi formation;the most significant is seen in those patients with adherence to medical treatment for hypocitraturia.

关 键 词：Kidney stones Renal stones Metabolic disorders Medical treatment CITRATE OXALATE LITHIASIS 

分 类 号：R692.4[医药卫生—泌尿科学]