CITRATE

作品数：224被引量：402H指数：10
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相关机构：厦门大学湖北省医药工业研究院山东大学启东市人民医院更多>>
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Transcriptome analysis reveals the common and specific pathways of citric acid accumulation in different citrus species
《Horticultural Plant Journal》2025年第2期520-534,共15页Jiaxian He Juan Sun Yue Huang Lun Wang Shengjun Liu Zhenghua Jiang Xia Wang Qiang Xu 
financially supported by the National Natural Science Foundation of China(Grant No.31925034);the National Key Research and Development Program of China(Grant No.2022YFF1003100);the Foundation of Hubei Hongshan Laboratory(Grant No.2021hszd016);Key project of Hubei provincial Natural Science Foundation(Grant No.2021CFA017)。
Citric acid is an important contributor to fruit flavor.The extremely significant differences in citric acid levels are observed among citrus species and varieties.The molecular basis of citric acid accumulation remai...
关键词：CITRUS Citric acid TRANSCRIPTOME Regulatory network Vacuolar acidification Citrate synthesis 
The Tricarboxylic Acid Cycle Metabolites for Cancer:Friend or Enemy
《Research》2025年第1期385-409,共25页Jie Wu Nian Liu Jing Chen Qian Tao Qiuqiu Li Jie Li Xiang Chen Cong Peng 
supported by grant nos.82073458,82173424,81974476,and 82221002 from the National Natural Science Foundation;by grant from The Scientific Research Program of FuRong Laboratory(no.2023SK2103);by the Science and Technology Innovation Program of Hunan Province(2021RC4013);as well as the key project in Hunan province(2024JJ3052).
The tricarboxylic acid(TCA)cycle is capable of providing sufficient energy for the physiological activities under aerobic conditions.Although tumor metabolic reprogramming places aerobic glycolysis in a dominant posit...
关键词：aerobic glycolysis tricarboxylic acid cycle tumor metabolic reprogramming amino acidstca tumor cells metabolic reprogramming ketoglutarate CITRATE 
Mechanism of action of Linggui Zhugan Decoction in treating non-alcoholic fatty liver disease using untargeted metabolomics approach
《Traditional Medicine Research》2025年第2期65-76,共12页Huan Pei Ren-Lin Li Xin-Ran Song Qian-Qian Wan Yu-Ming Wang Han-Zhou Li Wei-Quan Xu Jia-Bao Liao Wei-Bo Wen Jing Miao Huan-Tian Cui 
supported by the National Natural Science Foundation of China(82274424).
Background:Non-alcoholic fatty liver disease(NAFLD)is a liver disorder characterized by the accumulation and degeneration of fat in the liver cells,a condition that may further deteriorate and lead to cirrhosis and li...
关键词：NAFLD LGZGD untargeted metabolomics glycerophospholipid metabolism citrate cycle 
Intrinsically bioactive multifunctional Poly(citrate-curcumin) for rapid lung injury and MRSA infection therapy
《Bioactive Materials》2024年第11期158-173,共16页Tongtong Leng Long Zhang Junping Ma Xiaoyan Qu Bo Lei 
National Natural Science Foundation of China(grant No.52172288);Young Talent Support Plan of Xi'an Jiaotong University of China(grant No.QY6J003)。
Dysregulated inflammation after trauma or infection could result in the further disease and delayed tissue reconstruction.The conventional anti-inflammatory drug treatment suffers to the poor bioavailability and side ...
关键词：Bioactive materials Bioactive polymers Citrate polymer ANTI-INFLAMMATORY Inflammatory diseases 
A functional analysis of a resorbable citrate-based composite tendon anchor
《Bioactive Materials》2024年第11期207-220,共14页Arun Thirumaran Meletios-Nikolaos Doulgkeroglou Magesh Sankar Jeremiah T.Easley Ben Gadomski Anup Poudel Manus Biggs 
Foundation Ireland(SFI)and the European Regional Development Fund(Grant No.13/RC/2073).
Rapid and efficient tendon fixation to a bone following trauma or in response to degenerative processes can be facilitated using a tendon anchoring device.Osteomimetic biomaterials,and in particular,bio-resorbable pol...
关键词：CITRATE OSTEOINDUCTIVE Tendon anchor COMPOSITE 
Synergistic rheumatoid arthritis therapy by interrupting the detrimental feedback loop to orchestrate hypoxia M1 macrophage polarization using an enzyme-catalyzed nanoplatform
《Bioactive Materials》2024年第11期221-238,共18页Dong Guo Hui Liu Sheng Zhao Xinya Lu Haoyu Wan Yitao Zhao Xinzhi Liang Anbiao Zhang Mengyuan Wu Zhisheng Xiao Ning Hu Zhong Li Denghui Xie 
Science Foundation Ireland(SFI)and the European Regional Development Fund(Grant No.13/RC/2073).
Rapid and efficient tendon fixation to a bone following trauma or in response to degenerative processes can be facilitated using a tendon anchoring device.Osteomimetic biomaterials,and in particular,bio-resorbable pol...
关键词：CITRATE OSTEOINDUCTIVE Tendon anchor Composite 
Personalized composite scaffolds for accelerated cell-and growth factor-free craniofacial bone regeneration
《Bioactive Materials》2024年第11期427-439,共13页Mirae Kim Xinlong Wang Yiming Li Zitong Lin Caralyn P.Collins Yugang Liu Yujin Ahn Hsiu-Ming Tsal Joseph W.Song Chongwen Duan Yi Zhu Cheng Sun Tong-Chuan He Yuan Luo Russell R.Reid Guillermo A.Ameer 
National Research Foundation of Korea(2021R1A6A3A14039205)(Mirae Kim);National Institutes of Health/National Institute of Dental and Craniofacial Research(R01DE030480)(Russell R.Reid).
Approaches to regenerating bone often rely on integrating biomaterials and biological signals in the form of cells or cytokines.However,from a translational point of view,these approaches are challenging due to the so...
关键词：Craniofacial bone regeneration Composite scaffold Material-centric approach3D printing Citrate biomaterial 
A biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration
《Bioactive Materials》2024年第11期553-563,共11页Madeleine Goedegebuure Matthew I.Bury Xinlong Wang Pasquale Sanfelice Federico Cammarata Larry Wang Tiffany T.Sharma Nachiket Rajinikanth Vikram Karra Vidhika Siddha Arun K.Sharma Guillermo A.Ameer 
Center for Advanced Regenerative Engineering and the Department of Urology at the Feinberg School of Medicine at Northwestern University,the Division of Urology at Lurie Children's Hospital of Chicago;NIH grant R01EB026575 to A.K.S.and G.A.A,NIH grant R01DK109539 to A.K.S.,and T32 grant(EB031527)to G.A.A.
Chronic bladder dysfunction due to bladder disease or trauma is detrimental to affected patients as it can lead to increased risk of upper urinary tract dysfunction. Current treatment options include surgical interven...
关键词：Guided bladder tissue regeneration Mesenchymal stem cell Hematopoietic stem cell MICROTOPOGRAPHY NEOVASCULARIZATION 
Injectable citrate-based polyurethane-urea as a tug-of-war-inspired bioactive self-expansive and planar-fixing screw augmented bone-tendon healing
《Bioactive Materials》2024年第11期108-126,共19页Meihan Tao Zhou Fang Yuting Zhu Yan Ju Zhiguo Hou Meimei Fu Zhihui Lu Daozhang Cai Jian Yang Jinshan Guo 
Youth Talent of Guangdong Special Support Program(0620220207);Natural Science Foundation of China(Grant Nos.U21A2099,82272453,and 82102545);China Postdoctoral Science Foundation(Grant No.2022M721515);Basic and Applied Basic Research Project of Guangzhou City(202201011774);Open Program from Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Disease.
Inspired by tug-of-war,a game-changing bone-tendon fixation paradigm was developed.Specifically,injectable citrate-based bioactive self-expansive and planar-fixing screw(iCSP-Scr)consisting of reactive isocyanate(NCO)...
关键词：Polyurethane INJECTABLE Self-expansive Planar-fixing CITRATE 
Effect and safety of different doses of desloratadine citrate disodium in patients with chronic spontaneous urticaria in Chinese Han population
《Chinese Medical Journal》2024年第20期2483-2485,共3页Ke Xue Mengmeng Li Lei Wang Yi Sun Tongxiang Zeng Bing Liu Yong Cui 
Chronic spontaneous urticaria(CSU)is defined as the spontaneous appearance of wheals,angioedema,or both for more than six weeks due to known or unknown causes.The prevalence of CSU was found to be higher in Asian stud...
关键词：doses PATIENTS DISODIUM 
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