OSTEOINDUCTIVE

作品数：19被引量：44H指数：3
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相关领域：医药卫生更多>>
相关机构：安徽医科大学更多>>
相关期刊：《Bioactive Materials》《Open Journal of Stomatology》《Journal of Materials Science & Technology》《Journal of Wuhan University of Technology(Materials Science)》更多>>
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Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake
《International Journal of Oral Science》2024年第4期643-656,共14页Yawen Cheng Yuan Zhu Yaoshan Liu Xuenan Liu Yanan Ding Deli Li Xiao Zhang Yunsong Liu 
supported by grants from the National Natural Science Foundation of China(No.82170929 and 81970908 to Y.L.);the Beijing Natural Science Foundation(No.7222224 to X.Z.)。
Accumulating evidence has demonstrated that apoptotic vesicles(apoVs)derived from mesenchymal stem cells(MSCs;MSC-apoVs)are vital for bone regeneration,and possess superior capabilities compared to MSCs and other extr...
关键词：APO inductive enriched 
A functional analysis of a resorbable citrate-based composite tendon anchor
《Bioactive Materials》2024年第11期207-220,共14页Arun Thirumaran Meletios-Nikolaos Doulgkeroglou Magesh Sankar Jeremiah T.Easley Ben Gadomski Anup Poudel Manus Biggs 
Foundation Ireland(SFI)and the European Regional Development Fund(Grant No.13/RC/2073).
Rapid and efficient tendon fixation to a bone following trauma or in response to degenerative processes can be facilitated using a tendon anchoring device.Osteomimetic biomaterials,and in particular,bio-resorbable pol...
关键词：CITRATE OSTEOINDUCTIVE Tendon anchor COMPOSITE 
Synergistic rheumatoid arthritis therapy by interrupting the detrimental feedback loop to orchestrate hypoxia M1 macrophage polarization using an enzyme-catalyzed nanoplatform
《Bioactive Materials》2024年第11期221-238,共18页Dong Guo Hui Liu Sheng Zhao Xinya Lu Haoyu Wan Yitao Zhao Xinzhi Liang Anbiao Zhang Mengyuan Wu Zhisheng Xiao Ning Hu Zhong Li Denghui Xie 
Science Foundation Ireland(SFI)and the European Regional Development Fund(Grant No.13/RC/2073).
Rapid and efficient tendon fixation to a bone following trauma or in response to degenerative processes can be facilitated using a tendon anchoring device.Osteomimetic biomaterials,and in particular,bio-resorbable pol...
关键词：CITRATE OSTEOINDUCTIVE Tendon anchor Composite 
One-step co-doping of ZnO and Zn^(2+)in osteoinductive calcium phosphate ceramics with synergistic antibacterial activity for regenerative repair of infected bone defect被引量：2
《Journal of Materials Science & Technology》2023年第32期168-181,共14页Tinghan He Hongxu Chen Puxin Liu Hao Shi Xiujuan Xu Cong Feng Yuyi Wang Xiangfeng Li Ning Lei Yumei Xiao Xiangdong Zhu Jianguo Xu Xingdong Zhang 
the National Key Research and Development Program of China(Grant No.2022YFC2401801);National Science Foundation of China(Grant No.52002256);Major Project of Sichuan Science and Technology Department(Grant Nos.2022ZDZX0029 and 2021YFS0032);Sichuan University“Zero to one”Innovation Research Project(Grant No.2022SCUH0044).
How to endow bone grafts with long-term antibacterial activity and good bone regenerative ability to achieve the regenerative repair of infected bone defects has been the focus of the clinical treatment of osteomyelit...
关键词：Biphasic calcium phosphate ceramics Zinc oxide Zinc ion Antibacterial ability OSTEOINDUCTIVITY 
Triple-functional bone adhesive with enhanced internal fixation,bacteriostasis and osteoinductive properties for open fracture repair被引量：4
《Bioactive Materials》2023年第7期273-290,共18页Yusheng Yang Shenghui Su Shencai Liu Weilu Liu Qinfeng Yang Liangjie Tian Zilin Tan Lei Fan Bin Yu Jian Wang Yanjun Hu 
This work was supported by the Guangzhou Science and Technology Program Key Projects(No.202002020001);Science and Technology Planning Project of Guangdong Province(No.2020A0505100039);Autonomous region science and technology branch Xinjiang project plan(No.2022E02040);Clinical Key Specialty in Ningde City,Fujian Province.
At present,effective fixation and anti-infection implant materials represent the mainstay for the treatment of open fractures.However,external fixation can cause nail tract infections and is ineffective for fixing sma...
关键词：Open fracture Bone adhesive Internal fixation BACTERIOSTASIS OSTEOINDUCTION 
Continuously released Zn^(2+)in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties被引量：3
《Bioactive Materials》2023年第6期361-375,共15页Chunxu Li Fengbo Sun Jingjing Tian Jiahao Li Haidan Sun Yong Zhang Shigong Guo Yuanhua Lin Xiaodan Sun Yu Zhao 
supported by Tsinghua University-Peking Union Medical College Hospital Initiative Scientific Research Program(20191080871);the National Natural Science Foundation of China(82272464,82002314).
Long-term nonunion of bone defects has always been a major problem in orthopedic treatment.Artificial bone graft materials such as Poly(lactic-co-glycolic acid)/β-tricalcium phosphate(PLGA/β-TCP)scaffolds are expect...
关键词：3D printing Zinc submicron particles OSTEOINDUCTIVITY ANTI-INFLAMMATORY Bone defect repair 
Osteoinductive intramedullary implant as an adjunctive therapy for bone transport:A promising approach to accelerate bone defect healing
《Mechanobiology in Medicine》2023年第2期8-10,共3页Yuejun Lin Jiaming Yang Gang Li 
supported by grants from the National Natural Science Foundation of China(82172430);University Grants Committee,Research Grants Council of the Hong Kong Special Administrative Region,China(14113723,14108720,14121721,14202920,N_CUHK472/22,C7030-18G,T13-402/17-N and AoE/M-402/20);Health Medical Research Fund(HMRF)Hong Kong(17180831,08190416 and 09203436).
A recent study published in Nature Communications presents a unique approach using an osteoinductive intra-medullary(IM)implant as an adjunctive therapy for bone transport distraction osteogenesis.The study demon-stra...
关键词：Distraction osteogenesis Bone transport Bone morphogenetic protein-2 OSTEOINDUCTION Intramedullary nail 
Strategies of strengthening mechanical properties in the osteoinductive calcium phosphate bioceramics被引量：1
《Regenerative Biomaterials》2023年第1期561-573,共13页Qipeng Li Cong Feng Quanle Cao Wei Wang Zihan Ma Yonghao Wu Tinghan He Yangtian Jing Wenxuan Tan Tongxiao Liao Jie Xing Xiangfeng Li Ye Wang Yumei Xiao Xiangdong Zhu Xingdong Zhang 
supported by the National Key Research and Development Program of China(2021YFB3802100,2021YFB3802105);Major Project of Sichuan Science and Technology Department(2022ZDZX0029);the International Science and Technology Innovation Cooperation Project of Sichuan Province(2021YFH0131);National Natural Science Foundation of China(52002256);the Science and Technology Cooperation Program of Sichuan University and Panzhihua City(2021);Sichuan University‘Zero to one’Innovation Research Project(0082604151276).
Calcium phosphate(CaP)bioceramics are widely applied in the bone repairing field attributing to their excellent biological properties,especially osteoinductivity.However,their applications in load-bearing or segmental...
关键词：CaP ceramics strategy mechanical property OSTEOINDUCTIVITY enhancement 
Biomimetic,biodegradable and osteoinductive treated dentin matrix/α-calcium sulphate hemihydrate composite material for bone tissue engineering被引量：1
《Regenerative Biomaterials》2023年第1期1222-1232,共11页Runying Guo Rui Zhang Sirui Liu Yanyu Yang Wenhang Dong Meiyue Wang Hongyan Mi Mengzhe Liu Jingjing Sun Xue Zhang Yimeng Su Yiming Liu Di Huang Rui Li 
the National Natural Science Foundation of China(grant numbers 31670994,U1904145 and 81901039);Nature Science Foundation of Henan Province(grant numbers 182300410340,222300420569);Henan Medical Science and Technology Research Project(grant number SBGJ202002073,SBGJ202002075);Science and Technology Department of Science and Technology Research(grant number 182102310456);Henan Province Middle-Aged And Young Health Science and Technology Innovation Leader Training Project(grant number YXKC2021014);Scientific Research and Innovation Team of The First Affiliated Hospital of Zhengzhou University(grant number QNCXTD2023021);Union project of Medical and Technology Research Program of Henan Province(grant number LHGJ20190191).
It is still a huge challenge for bone regenerative biomaterial to balance its mechanical,biological and biodegradable properties.In the present study,a new composite material including treated dentin matrix(TDM)andα-...
关键词：bone defect treated dentin matrix α-calcium sulphate hemihydrate osteogenesis 
Decoupling the role of chemistry and microstructure in hMSCs response to an osteoinductive calcium phosphate ceramic
《Bioactive Materials》2023年第1期127-138,共12页V.P.Galván-Chacon D.de Melo Pereira S.Vermeulen H.Yuan J.Li P.Habibovic 
Calcium phosphates(CaP)are widely used synthetic bone graft substitutes,having bioactivity that is regulated by a set of intertwined physico-chemical and structural properties.While some CaPs have shown to be as effec...
关键词：Calcium phosphate MICROSTRUCTURE Chemical composition Mesenchymal stromal cells Osteogenic differentiation 
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