OSTEOINDUCTION

作品数:39被引量:122H指数:5
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相关领域:医药卫生更多>>
相关作者:韩建业余森麻西群于振涛李建磊更多>>
相关机构:西北有色金属研究院空军军医大学(第四军医大学)绍兴市人民医院更多>>
相关期刊:《Journal of Biomaterials and Nanobiotechnology》《Transactions of Nonferrous Metals Society of China》《Journal of Materials Science & Technology》《Journal of Wuhan University of Technology(Materials Science)》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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A 3D In-vitro model of the human dentine interface shows long-range osteoinduction from the dentine surface
《International Journal of Oral Science》2024年第2期225-237,共13页William Macalester Asme Boussahel Rafael O.Moreno-Tortolero Mark R.Shannon Nicola West Darryl Hill Adam Perriman 
supported by the Bristol Centre for Functional Nanomaterials and GlaxoSmithKline.
Emerging regenerative cell therapies for alveolar bone loss have begun to explore the use of cell laden hydrogels for minimally invasive surgery to treat small and spatially complex maxilla-oral defects.However,the or...
关键词:INTERFACE DEN SURFACE 
Role of dendritic cells in MYD88-mediated immune recognition and osteoinduction initiated by the implantation of biomaterials被引量:1
《International Journal of Oral Science》2023年第3期411-421,共11页Zifan Zhao Qin Zhao Hu Chen Fanfan Chen Feifei Wang Hua Tang Haibin Xia Yongsheng Zhou Yuchun Sun 
supported by the Beijing Training Project for the Leading Talents in S&T(Grant No.Z191100006119022);the National Key Program of the National Natural Science Foundation of China(Grant No.51705006);Capital’s Funds for Health Improvement and Research(2022-2Z-4106).
Bone substitute material implantation has become an important treatment strategy for the repair of oral and maxillofacial bone defects.Recent studies have shown that appropriate inflammatory and immune cells are essen...
关键词:IMPLANTATION BIOMATERIALS release 
Triple-functional bone adhesive with enhanced internal fixation,bacteriostasis and osteoinductive properties for open fracture repair被引量:4
《Bioactive Materials》2023年第7期273-290,共18页Yusheng Yang Shenghui Su Shencai Liu Weilu Liu Qinfeng Yang Liangjie Tian Zilin Tan Lei Fan Bin Yu Jian Wang Yanjun Hu 
This work was supported by the Guangzhou Science and Technology Program Key Projects(No.202002020001);Science and Technology Planning Project of Guangdong Province(No.2020A0505100039);Autonomous region science and technology branch Xinjiang project plan(No.2022E02040);Clinical Key Specialty in Ningde City,Fujian Province.
At present,effective fixation and anti-infection implant materials represent the mainstay for the treatment of open fractures.However,external fixation can cause nail tract infections and is ineffective for fixing sma...
关键词:Open fracture Bone adhesive Internal fixation BACTERIOSTASIS OSTEOINDUCTION 
Osteoinductive intramedullary implant as an adjunctive therapy for bone transport:A promising approach to accelerate bone defect healing
《Mechanobiology in Medicine》2023年第2期8-10,共3页Yuejun Lin Jiaming Yang Gang Li 
supported by grants from the National Natural Science Foundation of China(82172430);University Grants Committee,Research Grants Council of the Hong Kong Special Administrative Region,China(14113723,14108720,14121721,14202920,N_CUHK472/22,C7030-18G,T13-402/17-N and AoE/M-402/20);Health Medical Research Fund(HMRF)Hong Kong(17180831,08190416 and 09203436).
A recent study published in Nature Communications presents a unique approach using an osteoinductive intra-medullary(IM)implant as an adjunctive therapy for bone transport distraction osteogenesis.The study demon-stra...
关键词:Distraction osteogenesis Bone transport Bone morphogenetic protein-2 OSTEOINDUCTION Intramedullary nail 
Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity被引量:2
《Bioactive Materials》2023年第6期174-184,共11页Andrés García-García Sébastien Pigeot Ivan Martin 
supported by the Swiss National Science Foundation Div 3(Grant 31003A-179259 to I.M.);the National Centre of Competence in Research(NCCR)Molecular Systems Engineering(Grant 51NF40-141825 to I.M.).
The increasing recognition of the contribution of the immune system to activate and prime regeneration implies that tissue engineering strategies and biomaterials design should target regulation of early immunological...
关键词:IMMUNOMODULATION Bone tissue engineering Inflammation Hypertrophic cartilage matrices OSTEOINDUCTION 
Engineering Stem Cell Recruitment and Osteoinduction via Bioadhesive Molecular Mimics to Improve Osteoporotic Bone-Implant Integration
《Research》2023年第2期305-318,共14页Jiaxiang Bai Gaoran Ge Qing Wang Wenming Li Kai Zheng Yaozeng Xu Huilin Yang Guoqing Pan Dechun Geng 
This review work was supported by the National Natural Science Foundation of China(32222041,82072425,82072498,and 21875092);the Natural Science Foundation of Jiangsu Province(BK20220059 and BE2020666);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Special Project of Diagnosis and Treatment Technology for Key Clinical Diseases in Suzhou(LCZX202003);the“jiangsu Specially Appointed Professor”Program and Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX22_3217).
For patients with osteoporosis,the therapeutic outcomes of osteoimplants are substantially affected by the impaired proliferation,migration,and osteogenic differentiation abilities of bone marrow mesenchymal stem cell...
关键词:impaired osteoporosis MIMICS 
Whisker of biphasic calcium phosphate ceramics: Osteoimmunomodulatory behaviors被引量:1
《Nano Research》2022年第10期9169-9182,共14页Jinjie Wu Cong Feng Menglu Wang Hongfeng Wu Xiangdong Zhu Xiangfeng Li Xuening Chen Xingdong Zhang 
sponsored by the National Key Research and Development Program of China(No.2017YFB0702602);the National Nature Science Foundation of China(Nos.31971283 and 31670985);Sichuan Science and Technology Innovation Team of China(No.2019JDTD0008).
Immune systems play a critical role in the regulation of bone formation and homeostasis,which arouses a growing interest in the development of biomaterials that can modulate both immune response and osteogenesis.In th...
关键词:WHISKER macrophage polariztion OSTEOINDUCTION biphasic calcium phosphate surface structure 
Optimal regenerative repair of large segmental bone defect in a goat model with osteoinductive calcium phosphate bioceramic implants被引量:7
《Bioactive Materials》2022年第5期240-253,共14页Wei Zhi Xiaohua Wang Dong Sun Taijun Chen Bo Yuan Xiangfeng Li Xuening Chen Jianxin Wang Zhao Xie Xiangdong Zhu Kai Zhang Xingdong Zhang 
supported by the National Key R&D Program of China(2016YFC1102000);Research on repair technology and equipment of war injury(AWS17J004-02);the Science and Technology Innovation Seedling Project of Sichuan Province,China(2021057).
So far,how to achieve the optimal regenerative repair of large load-bearing bone defects using artificial bone grafts is a huge challenge in clinic.In this study,a strategy of combining osteoinductive biphasic calcium...
关键词:Calcium phosphate bioceramics Large segmental bone defects Bone regenerative repair OSTEOINDUCTION Mechanical stability 
Fabrication and biological evaluation of 3D-printed calcium phosphate ceramic scaffolds with distinct macroporous geometries through digital light processing technology被引量:4
《Regenerative Biomaterials》2022年第1期389-403,共15页Jing Wang Yitao Tang Quanle Cao Yonghao Wu Yitian Wang Bo Yuan Xiangfeng Li Yong Zhou Xuening Chen Xiangdong Zhu Chongqi Tu Xingdong Zhang 
sponsored by the National Key Research and Development Program of China(2017YFB0702600);National Natural Science Foundation of China(31971283,31670985);Sichuan Science and Technology Programs(2019JDTD0008,2021YFS0032).
Digital light processing(DLP)-based 3D printing technique holds promise in fabricating scaffolds with high precision.Here raw calcium phosphate(CaP)powders were modified by 5.5%monoalcohol ethoxylate phosphate(MAEP)to...
关键词:digital light processing(DLP) 3D printing pore structure OSTEOINDUCTION 
Preparation of multigradient hydroxyapatite scaffolds and evaluation of their osteoinduction properties被引量:4
《Regenerative Biomaterials》2022年第1期189-201,共13页Hao Huang Anchun Yang Jinsheng Li Tong Sun Shangke Yu Xiong Lu Tailin Guo Ke Duan Pengfei Zheng Jie Weng 
supported by the R&D Project in Key Areas of Guangdong(2019B010941002);the Key R&D Project for Social Development in Sichuan(2020YFS0455);Jiangsu Provincial Key Research and Development Program(CN)(BE2019608).
Porous hydroxyapatite(HA)scaffolds are often used as bone repair materials,owing to their good biocompatibility,osteoconductivity and low cost.Vascularization and osteoinductivity of porous HA scaffolds were limited i...
关键词:porous hydroxyapatite SCAFFOLD BIOCOMPATIBILITY OSTEOINDUCTION bone tissue engineering 
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