SCAFFOLD

作品数：646被引量：1779H指数：19
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A vascular endothelial growth factor–loaded chitosan-hyaluronic acid hydrogel scaffold enhances the therapeutic effect of adipose-derived stem cells in the context of stroke
《Neural Regeneration Research》2025年第12期3591-3605,共15页Zhijian Zheng Xiaohui Lin Zijun Zhao Qiang Lin Ji Liu Manli Chen Wenwen Wu Zhiyun Wu Nan Liu Hongbin Chen 
supported by a grant from the Excellent Young Scholars Cultivation Project of Fujian Medical University Union Hospital,No.2022XH026(to HC);Joint Funds for the Innovation of Science and Technology in Fujian Province,No.2019Y9058(to XL);the Natural Science Foundation of Fujian Province,No.2020J011017(to XL)。
Adipose-derived stem cell,one type of mesenchymal stem cells,is a promising approach in treating ischemia-reperfusion injury caused by occlusion of the middle cerebral artery.However,its application has been limited b...
关键词：adipose-derived stem cells chitosan hyaluronic acid HYDROGEL ISCHEMIA-REPERFUSION oxygen-glucose deprivation/reoxygenation stroke transient middle cerebral artery occlusion TRANSPLANTATION vascular endothelial growth factor 
Chitosan:A Scaffold Biomaterial in 3D Bone Tissue Engineering and Its Biological Activities
《集成技术》2025年第2期86-108,共23页Gurung Chetali Nawaz Aamir Udduttulla Anjaneyulu REN Peigen 
国家重点研发计划项目(2021YFA0719303);国家自然科学基金项目(32271166,32100572);广东省基础与应用基础研究基金项目(2024A1515013017);深圳市科技计划项目(JCYJ20200109115441918,KCXFZ2020122113400002,JCYJ20210324102013035,JCYJ20210324123610028)。
The ability to replicate the microenvironment of the human body through the fabrication of scaffolds is a significant achievement in the biomedical field.However,the search for the ideal scaffold is still in its infan...
关键词：CHITOSAN 3D bioprinting bone tissue engineering SCAFFOLD tissue regeneration chitosan derivative 
In situ synthesis,crystal structure,and magnetic characterization of a trinuclear copper complex based on a multi-substituted imidazo[1,5-a]pyrazine scaffold
《无机化学学报》2025年第3期597-604,共8页WANG Zhaodong 
A trinuclear copper complex [Cu_(3)(L2)_(2)(SO_(4))_(2)(H_(2)O)_(7)]·8H_(2)O(1)(HL2=1-hydroxy-3-(pyrazin-2-yl)-N-(pyrazin-2-ylmethyl)imidazo[1,5-a]pyrazine-8-carboxamide) with a multi-substituted imidazo[1,5-a]pyrazi...
关键词：amide ligand copper complex single crystal structure C-N coupling magnetic characterization 
Pyrrole and pyrrolidine analogs:The promising scaffold in discovery of pesticides
《Chinese Chemical Letters》2025年第3期113-124,共12页Anjing Liao Wei Sun Yaming Liu Han Yan Zhi Xia Jian Wu 
financial support from the National Natural Science Foundation of China(No.32072445);the Science and Technology Plan Project of Guizhou Province(Qiankehezhicheng[2024]the general 083);the Program of Introducing Talents to Chinese Universities(No.D20023);the Central Government Guides Local Science and Technology Development Fund Projects(Qiankehezhongyindi(2023)001);Key Agricultural Technology R&D Projects of the Xinjiang Production and Construction Corps(NYHXGG,2023AA602);the Frontiers Science Centre for Asymmetric Synthesis and Medicinal Molecules,Department of Education,Guizhou Province[Qianjiaohe KY(2020)004];the specific research fund of The Innovation Platform for Academicians of Hainan Province(No.SQ2020PTZ0009);。
Pyrrole is a heterocycle with four carbon atoms and a nitrogen atom,which is extensively used in the pesticide and pharmaceutical industries.In addition,it has a series of analogs such as pyrrolidine,pyrroline,and pyr...
关键词：PYRROLE PYRROLIDONE Agrochemicals Biological activity Structure-activity relationship 
A Distance-Adjustable 3D DNA Scaff old Accelerated Quadruped DNA Walker for the Photoelectrochemical Biosensing of RNA in Phytophthora Infestans
《Journal of Analysis and Testing》2025年第1期71-81,共11页Hui Yang Liying Ge Ziqing Liang Haoran Shen Yingju Liu Kaiyu He Weipeng Liu 
supported by the National Natural Science Foundation of China(32170100,32470085,22274059);Science and Technology Program of Guangzhou(2024A04J5241);Guangdong Basic and Applied Basic Research Foundation(2023A1515012871);Open Fund of Key Laboratory of Information Traceability for Agricultural Products,Ministry of Agriculture and Rural Aff airs(2023KF04)。
Phytophthora infestans,the causative agent of potato late blight,poses a destructive threat to global agricultural production.Herein,a 3D DNA scaff old is elaborately designed as DNA tracks for accelerating the walkin...
关键词：DNA walker Phytophthora infestans PHOTOELECTROCHEMICAL DNA scaffold RNA detection 
Biomechanical Study of Different Scaffold Designs for Reconstructing a Traumatic Distal Femur Defect Using Patient-Specific Computational Modeling
《Computer Modeling in Engineering & Sciences》2025年第2期1883-1898,共16页Hsien-Tsung Lu Ching-Chi Hsu Qi-Quan Jian Wei-Ting Chen 
funded by the TaipeiMedical University-National Taiwan University of Science and Technology joint research program under Grant No.TMU-NTUST-109-09.
Reconstruction of a traumatic distal femur defect remains a therapeutic challenge.Bone defect implants have been proposed to substitute the bone defect,and their biomechanical performances can be analyzed via a numeri...
关键词：Patient-specific modeling distal femur bone defect microstructure design finite element analysis 
3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration
《Nano-Micro Letters》2025年第2期18-45,共28页Ke Yao Gaoying Hong Ximin Yuan Weicheng Kong Pengcheng Xia Yuanrong Li Yuewei Chen Nian Liu Jing He Jue Shi Zihe Hu Yanyan Zhou Zhijian Xie Yong He 
supported by the Innovative Research Group Project of the National Natural Science Foundation of China(T2121004);Key Programme(52235007);National Outstanding Youth Foundation of China(52325504).
Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and hi...
关键词：3D printing Tough hydrogel scaffold Functional surface structure Tissue regeneration BIOMATERIALS 
Mechanistic Analysis of Porous Iron Scaffold Degradation in Cancellous Bone Structure Subjected to Dynamic Simulated Body Fluid
《Journal of Bionic Engineering》2025年第1期306-321,共16页Muhammad Azfar Noordin Abdul Hakim Md Yusop Ardiyansyah Syahrom Amir Putra Md Saad 
funded by the Ministry of Higher Education,Malaysia under the Fundamental Research Grant Scheme(FRGS/1/2018/TK03/UTM/02/8).
This work examines the impact of incorporating the physiological conditions of human cancellous bone,by integrating similar porosity of porous Fe with the cancellous bone under dynamic immersion test.All of the porous...
关键词：Dynamic immersion test Cancellous bone Physiological activities Degradation rate Porous Fe 
Synthesis of ordered mesoporous crystalline boron phosphate scaffold with double diamond surface structure
《Science China Chemistry》2025年第2期590-600,共11页Chao Wang Wen-Duo Lu Jiao Wang Shunai Che An-Hui Lu Lu Han 
supported by the National Natural Science Foundation of China(21733002,22108028,22373074);Fundamental Research Funds for the Central Universities.
Ordered mesoporous materials have received great attention due to their well-defined pore structures and potential applications in catalysis,adsorption,separation,drug delivery,etc.Although various compositions of mes...
关键词：boron phosphate mesoporous material SELF-ASSEMBLY block copolymer catalyst 
Enhancing angiogenesis and osseointegration through a double gyroid Ti6Al4V scaffold with triply periodic minimal surface
《Bio-Design and Manufacturing》2025年第1期36-54,I0013-I0017,共24页Hao Liu Hao Chen Bin Sun Danyang Fan Aobo Zhang Hanqiang Liu Hexiang Wei Wenbo Yang Yongyue Li Peng Xia Qing Han Jincheng Wang 
supported bythe National Natural Science Foundation of China(Nos.U23A20523,82272504,and 82072456);the Department of Science and Technology of Jilin Province,China(Nos.20210101439JC,20210101321JC,20220204119YY,202201ZYTS131,202201ZYTS129,20230204114YY,YDZJ202201ZYTS505,and YDZJ202301ZYTS076);the Special Program for Science and Technology Personnel of Changchun(No.ZKICKJJ2023015);the Key Training Plan for Outstanding Youth of Jilin University(No.419070623036);the Research Fund of the First Hospital of Jilin University(No.2021-zl-01);the Graduate Innovation Fund of Jilin University(No.2024CX125);the Foun-dation of National Center for Translational Medicine(Shanghai)SHU Branch,China(No.SUITM-202405).
The pore structure of porous scaffolds plays a crucial role in bone repair.The prevalent bone implant structure in clinical practice is the traditional cubic structure.However,the traditional cubic structure exhibits ...
关键词：Double gyroid Triply periodic minimal surface OSSEOINTEGRATION ANGIOGENESIS 
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