Osteoinductive intramedullary implant as an adjunctive therapy for bone transport:A promising approach to accelerate bone defect healing  

作　　者：Yuejun Lin Jiaming Yang Gang Li 

机构地区：[1]Stem Cells and Regenerative Medicine Laboratory,Li Ka Shing Institute of Health Sciences,The Chinese University of Hong Kong,Prince of Wales Hospital,Shatin,Hong Kong SAR,PR China [2]Musculoskeletal Research Laboratory,Department of Orthopaedics&Traumatology,Faculty of Medicine,The Chinese University of Hong Kong,Prince of Wales Hospital,Shatin,Hong Kong SAR,PR China [3]The CUHK-ACC Space Medicine Centre on Health Maintenance of Musculoskeletal System,The Chinese University of Hong Kong Shenzhen Research Institute,Shenzhen,PR China

出　　处：《Mechanobiology in Medicine》2023年第2期8-10,共3页力学生物学与医学（英文）

基　　金：supported by grants from the National Natural Science Foundation of China(82172430);University Grants Committee,Research Grants Council of the Hong Kong Special Administrative Region,China(14113723,14108720,14121721,14202920,N_CUHK472/22,C7030-18G,T13-402/17-N and AoE/M-402/20);Health Medical Research Fund(HMRF)Hong Kong(17180831,08190416 and 09203436).

摘　　要：A recent study published in Nature Communications presents a unique approach using an osteoinductive intra-medullary(IM)implant as an adjunctive therapy for bone transport distraction osteogenesis.The study demon-strates that this innovative technique achieves early bony bridging,eliminates pin tract infections,and prevents docking site non-union,offering significant potential for the treatment of large bone defects.The study also highlights an additive effect of the osteoinductive IM implant on distraction osteogenesis for managing bone defect.

关 键 词：Distraction osteogenesis Bone transport Bone morphogenetic protein-2 OSTEOINDUCTION Intramedullary nail 

分 类 号：R68[医药卫生—骨科学]