白内障超声乳化吸除术联合人工晶状体植入术中使用吲哚菁绿的影响  

Effect of Indocyanine Green on Phacoemulsification Combined Intraocular Lens Implantation

作　　者：刘婕 顾永辉[1] 鲁曦婷[1] 王莹[1] 李之喆[1] LIU Jie;GU Yonghui;LUXiting;WANG Ying;LI Zhizhe(Suzhou Municipal Hospital Headquarters,Suzhou 215002,China;不详)

机构地区：[1]苏州市立医院本部,江苏苏州215002

出　　处：《中外医学研究》2021年第34期25-28,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究吲哚菁绿在白内障超声乳化吸除术(phacoemulsification,PHACO)联合人工晶状体(intraocular lens,IOL)植入术中的影响。方法:选取2019年4月-2020年8月在苏州市立医院本部住院的单纯老年性白内障患者120例(120只眼),随机分为试验组(60只眼)和对照组(60只眼),所有患者均行PHACO+IOL植入术,试验组术中使用吲哚菁绿,对照组术中未使用吲哚菁绿。应用非接触式自动角膜内皮细胞显微镜行角膜内皮照相。观察试验组术后染料是否残存,对比两组术中撕囊情况,两组患者眼部一般情况(术后角膜水肿及前房炎症反应),术后1 d、1个月、3个月的最佳矫正视力(BCVA)、眼压及角膜内皮细胞指标[中央角膜内皮细胞密度(CCD)、变异系数(CV)、六角形细胞比例(6A)、平均内皮细胞面积(AVE)]。结果:试验组撕囊成功率为95.0%,对照组为76.7%。两组对比差异有统计学意义(P<0.05)。术后试验组染料无残存,两组角膜水肿、前房炎症反应比较差异均无统计学意义(P>0.05),两组术后1 d、1个月、3个月BCVA、眼压、CCD、CV、6A、AVE比较差异均无统计学意义(P>0.05)。结论:PHACO+IOL植入术中使用吲哚菁绿染色前囊膜安全有效,对角膜内皮无明显影响,能提高撕囊成功率,减少并发症。Objective:To study the effect of Indocyanine Green on phacoemulsification(PHACO)combined intraocular lens(IOL)implantation.Method:A total of 120 patients(120 eyes)with simple senile cataract hospitalized in Suzhou Municipal Hospital Headquarters from April 2019 to August 2020 were selected and randomly divided into experimental group(60 eyes)and control group(60 eyes).All patients were treated with PHACO+IOL implantation,Indocyanine Green was used in the experimental group and Indocyanine Green was not used in the control group.Non-contact automatic corneal endothelium cell microscope was used for corneal endothelium photography.The experimental group was observed whether the dye remained after operation,the intraoperative capsulorhexis and the general conditions of the eyes(postoperative corneal edema and anterior chamber inflammatory reaction)of the two groups were compared.Best corrected visual acuity(BCVA),intraocular pressure and corneal endothelial cell index[central corneal endothelial cell density(CCD),coefficient of variation(CV),proportion of hexagonal cells(6A),mean endothelial cell area(AVE)]at 1 d,1 month and 3 months after surgery were compared.Result:The success rate of capsulorhexis was 95.0%in the experimental group and 76.7%in the control group.The difference between the two groups was statistically significant(P<0.05).No dyes remained in the experimental group after surgery.There were no statistically significant differences in corneal edema and anterior chamber inflammatory reaction between the two groups(P>0.05),and there were no statistically significant differences in BCVA,intraocular pressure,CCD,CV,6A and AVE between the two groups at 1 d,1 month and 3 months after surgery(P>0.05).Conclusion:The Indocyanine Green staining of the anterior capsule membrane during PHACO+IOL implantation is safe,effective and convenient.It has no obvious effect on the corneal endothelium.It can improve the success rate of capsulorhexis,and reduce complications.

关 键 词：吲哚菁绿 白内障 超声乳化 角膜内皮 

分 类 号：R779.66[医药卫生—眼科]