Expressions and correlation of blood fibrinogen and IL-33 in patients with cerebral infarction combined with moderate-to-severe periodontitis  

作　　者：Zhuang-Zhi Wu Si-Qi Chen Xiao-Ning He 

机构地区：[1]Department of Stomatology,The Second Affiliated Hospital of Hainan Medical University,Haikou 570100,China

出　　处：《Journal of Hainan Medical University》2021年第23期26-30,共5页海南医学院学报（英文版）

基　　金：Natural science fund project of Hainan Province(No.819MS125)。

摘　　要：Objective:To observe the serum levels of Fibrinogen(Fg),Interleukin-33(IL-33)in patients with cerebral infarction and periodontitis,and to explore the relationship of cerebral infarction and periodontitis.Methods:104 subjects were included in this study.Among them,23 were patients with CI and CP(group CI+CP),28 with CI(group CI),28 with CP(group CP)and 25 were healthy volunteers(group H).The periodontal indexes and the serum levels of Fg and IL-33 were measured.Results:In groups of CI+CP,CP and CI the Fg and IL-33 were significantly higher than those in the group H(P<0.01).In groups of CI+CP the Fg and Il-33 was higher than group CI and CP(P<0.05).Conclusion:In patients with cerebral infarction with periodontitis,the levels of fibrinogen and interleukin-33 were both increased,and their concentrations were in direct proportion to the periodontal indexes。

关 键 词：Cerebral infarction PERIODONTITIS FIBRINOGEN INTERLEUKIN-33 

分 类 号：R74[医药卫生—神经病学与精神病学]