十二指肠间质瘤两种局部切除术的疗效对比分析  

A comparision between two different local resections for the treatment of duodenal stromal tumors

作　　者：袁静雅 石岩岩[2] 邴运韬 修典荣[1] Yuan Jingya;Shi Yanyan;Bing Yuntao;Xiu Dianrong(Department of General Surgery,Peking University Third Hospital,Beijing 100091,China;Clinical Epidemiology Research Center,Peking University Third Hospital,Beijing 100091,China)

机构地区：[1]北京大学第三医院普通外科,100091 [2]北京大学第三医院临床流行病学研究中心,100091

出　　处：《中华普通外科杂志》2021年第12期915-918,共4页Chinese Journal of General Surgery

基　　金：北京大学第三医院青年孵育基金(BYSYFY2021040)。

摘　　要：目的探讨两种不同的局部切除术治疗十二指肠间质瘤的安全性和临床疗效。方法回顾性分析2015年5月至2021年5月因十二指肠间质瘤行腹腔镜为主的十二指肠局部切除术25例患者的临床病理资料,其中8例接受楔形切除术,17例行区段切除术。结果与区段切除组相比,楔形切除组的手术时间明显较短[(202±43)min比(299±128)min,t=-2.814,P=0.010]。楔形切除组的中位出血量为20(10~50)ml,区段切除组为30(15~100)ml,差异无统计学意义(t=-1.128,P>0.05)。与区段切除组相比,楔形切除组患者的术后住院时间短[7(9~11)d比14(10~28)d,t=-2.66,P=0.008]。两组术后并发症和胃排空障碍的发生情况差异无统计学意义(P>0.05)。结论依据不同肿瘤位置选择的十二指肠间质瘤楔形切除与区段切除两种术式在安全性和临床疗效方面均令人满意。Objective To investigate the safety and clinical efficacy of laparoscopy dominated approaches to two different local resections for duodenal stromal tumors.Methods From May 2015 to May 202125 duodenal stromal tumors cases were allocated to wedged resection group(8 cases)and segmental resection(17cases).Results Compared with the segmental resection group,the operative time in the wedge resection group was significantly shorter[(202±43)min vs.(299±128)min,t=-2.814,P=0.010].The intraoperative blood loss was 20(10-50)ml in the wedge resection group and 30(15-100)ml in the segmental resection group(t=-1.128,P>0.05).Patients in the wedge resection group had a significantly shorter postoperative hospital stay,7(9-11)days vs.14(10-28)days,t=-2.66,P=0.008.There was no difference in the incidence of postoperative complications and gastric emptying disorders between the two groups(P>0.05).Conclusion In spite of laparoscopic,robotic or open approaches,wedge resection and segmental resection based on anatomic location for duodenal stromal tumors are both safe and satisfactory.

关 键 词：胃肠道间质肿瘤 十二指肠 腹腔镜 

分 类 号：R735[医药卫生—肿瘤]