腹腔镜胃功能保留术与根治术治疗早期胃癌的临床比较  

Clinical comparison of laparoscopic gastric-function-preserving surgery and radical resection for early gastric cancer

作　　者：邓褫夺 林学祥 李俊锐 张慧 Deng Chiduo;Lin Xuexiang;Li Junrui;Zhang Hui(Department of General surgery,Guidong people’s Hospital of Guangxi Zhuang Autonomous Region,Guangxi 543000,China;Department of Gastroenterology,Inner Mongolia People’s Hospital,Inner Mongolia 010017,China)

机构地区：[1]广西壮族自治区桂东人民医院普外科,543000 [2]内蒙古自治区人民医院,010017

出　　处：《中华普外科手术学杂志（电子版）》2021年第6期665-667,共3页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)

基　　金：内蒙古自治区卫计委课题(201301007)。

摘　　要：目的比较腹腔镜胃功能保留术与根治术治疗早期胃癌的临床效果。方法回顾性分析2015年7月至2019年12月82例早期胃癌患者病例资料,根据术式不同分为两组,将接受腹腔镜胃功能保留术的42例患者纳入保留组,将接受腹腔镜根治术的40例患者纳入根治组。采用SPSS 23.0统计分析软件,符合正态分布的手术相关指标、生存质量与营养状况以(x±s)表示,采用独立t检验;并发症以率表示,采用χ^(2)检验,P<0.05为差异有统计学意义。结果保留组手术时间比根治组长,淋巴结清扫数量、术中出血量比根治组少,肛门排气时间、住院时间比根治组短,差异均有统计学意义(P<0.05)。术后6个月保留组GLQI、MNA评分均比根治组高(P<0.05)。两组术后并发症总发生率比较(14.3%vs.17.5%),差异无统计学意义(P>0.05)。结论与腹腔镜胃癌根治术相比,腹腔镜胃功能保留术有助于早期胃癌患者术后恢复,并可有效改善其营养状况及生存质量,但在降低术后并发症等方面无明显优势。Objective To compare the clinical outcome between the laparoscopic gastric-function-preserving surgery and radical resection for early gastric cancer.Methods The data of 82 patients with early gastric cancer underwent the gastric resection from July 2015 to December 2019 were analyzed retrospectively.According to different surgical procedures,they were divided into the retention group who received the laparoscopic gastric function preservation(n=42 cases),and the radical group who underwent laparoscopic radical resection(n=40 cases).Statistical analysis were performed by using SPSS23.0 software.The data of normally distributed operation-related indexes,quality of life and nutritional status were expressed as,and the difference between the two groups were examined by using t test.Complications expressed as the rate were examined by usingχ^(2) test.A P value of<0.05 was considered as statistically significant difference.Results Compared with the radical group,much less harvested lymph nodes and intraoperative bleeding,increased operational time and shorter time of anal exhaust and hospitalization were observed respectively in the retention group(P<0.05).The scores of GLQI and MNA in the retention group were higher than those in the radical group on 6 months after surgery(P<0.05).There was no significant difference between two groups in terms of the incidence of postoperative complications(14.3%vs.17.5%,P>0.05).Conclusion In the treatment of early gastric cancer,laparoscopic gastric-function-preserving surgery could improve the nutritional status and the quality of life of patients compared with laparoscopic radical gastrectomy,however without obvious advantage in reducing postoperative complications.

关 键 词：胃肿瘤 腹腔镜 手术后并发症 胃功能保留术 根治术 

分 类 号：R73[医药卫生—肿瘤]