Opportunities for agent based modeling of retinal stem cell transplantation  

作　　者：Larissa M.DePamphilis Troy Shinbrot Maribel Vazquez 

机构地区：[1]Department of Biomedical Engineering,Rutgers,The State University of New Jersey,Piscataway,NJ,USA

出　　处：《Neural Regeneration Research》2022年第9期1978-1980,共3页中国神经再生研究（英文版）

基　　金：supported by the US National Science Foundation(NSF CBET 180441);the US National Institutes of Health(NEI 1R21 EY031439-01)(to MV).

摘　　要：Late stage blindness and visual impairment(BVI)affects over 400 mi l l ion adul ts worldwide.These disabilities severely impact the ability of adults to function independently,reduce their quality of life,and worsen socio-economic burdens on health care systems.Importantly,the World Health Organization projects worldwide BVI from degenerated retina to more than double by the year 2050(Bourne et al.,2021).To understand the clinical problem,consider Figure 1A depicting the retina’s seven neuronal cell types that interconnect across three nuclear layers.Retinal photoreceptors of the outer nuclear layer(ONL)are light sensitive neurons that absorb and convert photons into bioelectrical signals.

关 键 词：FIGURE outer CONVERT 

分 类 号：R779.6[医药卫生—眼科]