多原发性肺癌诊疗的研究进展  

Research progress in diagnosis and treatment of multiple primary lung cancer

作　　者：孙芩玲 黄云超[1] 赵光强[1] 叶联华[1] SUN Qinling;HUANG Yunchao;ZHAO Guangqiang;YE Lianhua(Department of Thoracic Surgery,The Third Affiliated Hospital of Kunming Medical University,Yunnan Cancer Hospital,Kunming,650000,P.R.China)

机构地区：[1]昆明医科大学第三附属医院云南省肿瘤医院胸外一科,昆明650000

出　　处：《中国胸心血管外科临床杂志》2022年第1期127-132,共6页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：国家自然科学基金(81860325);云南省高层次卫生计生技术人才培养项目(L-2017006);云南省卫生科技计划项目(2018NS0071)。

摘　　要：随着疾病谱变化和检查技术进步,临床上对肺部多发结节、肿块进行检查时,发现多原发性肺癌(multiple primary lung cancer,MPLC)的检出率有逐渐增多的趋势,患病率也越来越高。MPLC与其它肺部疾病或肺部癌变在治疗及预后上有明显差异,多建议尽早手术,因此需术前或治疗过程中对MPLC做出准确判断。新近发展的分子和基因组学方法有可能更好地确定多发性病变之间的关系,人工智能可以作为一种相关的诊断辅助手段,在多发性肺结节的诊断中显示更准确和客观的结果。该文通过总结最新的MPLC的诊断研究(包括病理分析、影像学),分析手术治疗方式,展望MPLC诊治未来的研究方向,以期为MPLC的研究提供借鉴和参考。With the changes in the disease spectrum and the advancement of examination technology,the detection rate of multiple primary lung cancers(MPLC)is gradually increasing when multiple nodules and masses in the lung are examined clinically.MPLC has significant distinction with other types of lung diseases or lung cancers in the treatment and prognosis.In most cases,patients would be recommended to undergo the surgery as soon as possible which means that the accurate diagnosis should be made before surgery or during treatment.The newly developed molecular and genomic methods are more likely to better determine the relationship between multiple lesions.Artificial intelligence can be used as a related diagnostic aid to show more accurate and objective results in the diagnosis of multiple pulmonary nodules.This review summarizes the latest MPLC diagnostic research(including pathological analysis,imaging),analyzes surgical treatment methods,and looks forward to the future research direction of MPLC diagnosis and treatment,in order to provide reference for MPLC research.

关 键 词：多原发性肺癌 诊断 治疗 综述 

分 类 号：R734.2[医药卫生—肿瘤]