低频重复经颅磁刺激治疗癫痫的临床疗效观察  

Clinical Efficacy Observation of Low-Frequency Repetitive Transcranial Magnetic Stimulation in Epilepsy Treatment

作　　者：王服艳 赵广燕 杜冬青[1] Wang Fu-yan;Zhao Guang-yan;Du Dong-qing(Jining Psychiatric Hospital,Jining 272051,Shandong Province,China)

机构地区：[1]济宁市精神病防治院,山东济宁272051

出　　处：《中国社区医师》2022年第1期48-50,共3页Chinese Community Doctors

摘　　要：目的:探讨低频重复经颅磁刺激治疗癫痫的临床疗效。方法:2019年5月-2020年5月收治癫痫患者80例,随机分为两组。观察组给予低频重复经颅磁刺激加常规药物治疗,对照组仅给予常规药物治疗,比较两组患者临床疗效、简易精神状态检查量表(MMSE)评分及生活质量评分。结果:治疗8周后,观察组治疗总有效率、MMSE评分均高于对照组,癫痫发作频率及不良反应发生率均低于对照组,差异均有统计学意义(P<0.05);观察组治疗后生活质量各项评分均高于对照组,差异有统计学意义(P<0.05)。结论:低频重复经颅磁刺激联合抗癫痫药物治疗,可有效降低癫痫发作频率,在一定程度上改善认知功能,提高患者的生活质量,且不良反应发生率较低。Objective:To explore the clinical efficacy of low-frequency repetitive transcranial magnetic stimulation in the treatment of epilepsy.Methods:From May 2019 to May 2020,80 patients with epilepsy were selected and randomly divided into two groups.The observation group was treated with low-frequency repetitive transcranial magnetic stimulation and conventional medication.The control group was only given routine medication.The clinical efficacy,mini-mental state examination(MMSE)score and quality of life score of patients between the two groups were compared.Results:After 8 weeks of treatment,the total effective rate and MMSE score in the observation group were higher than those in the control group,and the frequency of seizures and the incidence of adverse reactions were lower than those in the control group,the difference was statistically significant(P<0.05).After treatment,the scores of quality of life in the observation group were higher than those in the control group,the difference was statistically significant(P<0.05).Conclusion:Low-frequency repetitive transcranial magnetic stimulation combined with antiepileptic drugs can effectively reduce the frequency of seizures,improve cognitive function to a certain extent,improve the quality of life of patients,and the incidence of adverse reactions is low.

关 键 词：低频重复经颅磁刺激 癫痫 临床疗效 认知功能 生活质量 

分 类 号：R742.1[医药卫生—神经病学与精神病学]