神经心理评估的新进展:认知功能与脑淀粉样蛋白沉积的关系  

New advances in neuropsychological assessment:the relationship between cognitive function and brain amyloid deposition

作　　者：黄艳露 郭起浩 Huang Yanlu;Guo Qihao(Department of Gerontology,Shanghai Jiao Tong University Affiliated Sixth People's Hospital)

机构地区：[1]上海交通大学附属第六人民医院老年病科,上海200233

出　　处：《重庆医科大学学报》2021年第11期1287-1290,F0002,共5页Journal of Chongqing Medical University

基　　金：国家重点研发计划资助项目(编号:2016YFC1306305、2018YFE0203600)。

摘　　要：阿尔茨海默病(Alzheimer’s disease,AD)是一种退行性疾病。在早期阶段,AD的特征是大脑中β淀粉样蛋白(βamyloid,Aβ)和tau蛋白的聚集和记忆力减退。本文总结了脑内Aβ与认知功能的关系,对当前Aβ如何影响认知功能(记忆、执行、语言)的研究进行了综述,同时对今后研究趋势进行展望,为Aβ沉积的识别提供新思路。Alzheimer’s disease(AD)is a kind of degenerative disease. In the early stage,AD is characterized by the aggregation ofβ amyloid(Aβ)and tau proteins in the brain and memory loss. This paper summarizes the relationship between Aβ and cognitive function of the brain,reviews current research on how Aβ affects cognitive function(memory,execution and language),and also provides an outlook on future research trends to provide new ideas for the identification of Aβ deposition.

关 键 词：阿尔茨海默病 Β淀粉样蛋白 认知功能 

分 类 号：R74[医药卫生—神经病学与精神病学]