丙氨酸转氨酶的参考区间与临床诊疗决策阈值的辨析  

Differentiate between the reference interval and the clinical diagnosis and treatment decision threshold for alanine aminotransferase

作　　者：王蓓丽 潘柏申 Wang Beili;Pan Baishen(Department of Laboratory,Zhongshan Hospital,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属中山医院检验科,上海200032

出　　处：《中华肝脏病杂志》2021年第12期1213-1217,共5页Chinese Journal of Hepatology

基　　金：上海市临床重点专科建设项目(shslczdzk03302);国家自然基金青年项目(81902139)。

摘　　要：关于是否应调低ALT参考上限的争论已持续了近20年,然而,参考区间与诊疗决策阈值的概念、建立方法及应用范围是不同的,现对此进行辨析与相关研究回顾,以帮助更好地应用参考区间与诊疗决策阈值。The debate about whether the upper limit of normal for ALT should be lowered has been going on for nearly 20 years.However,the concept,the establishment method,and the application scope of reference interval are different from those of the clinical diagnosis and treatment decision threshold.We will differentiate the two concepts and review the related publications to help clinicians better apply the reference interval and the decision threshold for disease diagnosis and treatment.

关 键 词：丙氨酸转氨酶 肝病 参考区间 阈值 

分 类 号：R575[医药卫生—消化系统] R446[医药卫生—内科学]