2016-2018年郑州市城市人群结直肠癌筛查流行病学分析  

Epidemiological analysis of colorectal cancer screening in Zhengzhou City from 2016to 2018

作　　者：曹旸[1] 李安州[1] 许迎喜 师卫翔 孟可 陈航[1] 姜伟 王丛丛 李增辉 李培培 李蕾[1] 吴红艳[1] 王晓翠 马展 CAO Yang;LI An-zhou;XU Ying-xi;SHI Wei-xiang;MENG Ke;CHEN Hang;JIANG Wei;WANG Cong-cong;LI Zeng-hui;Li Pei-pei;LI Lei;WU Hong-yan;WANG Xiao-cui;MA Zhan(Third Ward of Oncology,Zhengzhou Third People's Hospital/Zhengzhou Cancer Hospital/Cancer Hospital Affiliated to Henan University/Zhengzhou Cancer Diagnosis and Treatment Quality Control Center/Zhengzhou Cancer Prevention and Treatment Office/Zhengzhou Cancer Center,Zhengzhou450000,China;Disease Cantrol Department of Zhengzhou Health Committee,Zhengzhou450000,China;Zhengzhou Yihe Hospital,Zhengzhou450000,China)

机构地区：[1]郑州市第三人民医院肿瘤内科三病区/郑州市肿瘤医院/河南大学附属肿瘤医院/郑州市肿瘤诊疗质量控制中心/郑州市肿瘤防治办公室/郑州市癌症中心,河南郑州450000 [2]郑州市卫生健康委员会疾控处,河南郑州450000 [3]郑州颐和医院疾控科,河南郑州450000 [4]郑州颐和医院放疗科,河南郑州450000

出　　处：《中华肿瘤防治杂志》2021年第23期1780-1784,共5页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的评估2016-2018年郑州市结直肠癌筛查高危人群情况,为更好开展癌症早诊早治工作提供材料支持,为郑州市癌症防治提供有效信息.方法对2016-2018年郑州市城市(10个辖区及6个县级市)40~75岁户籍人口进行结直肠癌风险问卷评估.评估得出的结直肠癌高危人群,再采用无痛结直肠镜进行复筛检测,根据结直肠镜病理判定结果探讨结直肠癌筛查评价效果.结果2016-2018年初筛结直肠癌高危人群19115人,高风险检出率为19.33%:其中,男7757人(40.6%),女11358人(59.4%);平均年龄(57.61±7.73)岁,中位年龄57岁.不同性别(χ^(2)=4.946,P=0.026)、不同年龄(χ^(2)=88.108,P<0.001)、不同文化程度(χ^(2)=741.680,P<0.001)和不同职业(χ^(2)=998.671,P<0.001)人群高危检出率差异均有统计学意义.多因素Logistic回归分析显示,评估为高危人群的风险,男性是女性的1.351倍(OR=1.351,95%CI:1.073~1.701),未受教育、小学和初中人群分别是大学及以上学历人群的3.175倍(OR=3.175,95%CI:1.563~6.449)、3.173倍(OR=3.173,95%CI:2.083~4.835)和1.714倍(OR=1.714,95%CI:1.241~2.367).郑州市城市高危人群结直肠癌检查依从率为23.49%.结论性别、年龄等因素是结直肠癌高危人群的影响因素,男性与受教育程度较低的人群是结直肠癌的高危人群.Objective To evaluate the high-risk population of colorectal cancer screening in Zhengzhou from 2016to 2018,provide material support for better carrying out the project of early diagnosis and treatment of cancer,and offer information for cancer prevention and control in Zhengzhou.Method A questionnaire was conducted to assess the risk of colorectal cancer in 40-75registered residence population in Zhengzhou City(10districts and 6county-level cities)from 2016to 2018.The high-risk population of colorectal cancer was evaluated,and then the painless colorectal colonoscopy was used for rescreening detection.The evaluation effect of colorectal cancer screening was discussed according to the pathological judgment results of colorectal colonoscopy.Results From 2016to 2018,19115patients were screened as high-risk population of colorectal cancer,with 19.33%of high-risk detection rate.Among them,7757were males,accounting for 40.6%of the high-risk population,and 11358were females,accounting for 59.4%.The average age was(57.61±7.73)years,and the median age was 57years.There were significant differences in the detection rate of high-risk groups with different genders(χ^(2)=4.946,P=0.026),different ages(χ^(2)=88.108,P<0.001),different educational levels(χ^(2)=741.680,P<0.001)and different occupations(χ^(2)=998.671,P<0.001).Multivariate logistic regression analyses showed that the risk of men assessed as high-risk groups was 1.351times higher than that of women(OR=1.351,95%CI:1.073-1.701);the risks of people with no education,receiving primary education and secondary education assessed as high-risk groups were 3.175times(OR=3.175,95%CI:1.563-6.449),3.173times(OR=3.173,95%CI:2.083-4.835)and 1.714times(OR=1.714,95%CI:1.241-2.367),respectively higher than that of people with college degree or above.The compliance rate of colorectal cancer examination in urban high-risk population in Zhengzhou was 23.49%.Conclusions Gender and age are the influencing factors.

关 键 词：结直肠癌 筛查 早诊早治 高危人群 郑州 

分 类 号：R735.3[医药卫生—肿瘤]