MR加速器治疗前列腺癌形状自适应标准操作流程——国家癌症中心/中国医学科学院肿瘤医院经验介绍  

The standard adapt-to-shape workflow for prostate cancer on MR-linac—Experience from National Cancer Institute/Cancer Hospital,Chinese Academy of Medical Sciences

作　　者：卢宁宁 田源 覃仕瑞 陈佳赟 王淑莲 李晔雄 Lu Ningning;Tian Yuan;Qin Shirui;Chen Jiayun;Wang Shulian;Li Yexiong(Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京100021

出　　处：《中华放射肿瘤学杂志》2022年第1期15-19,共5页Chinese Journal of Radiation Oncology

基　　金：中国医学科学院中央级公益性科研院所基本科研业务费专项资金资助(健康长寿专项2021-JKCS-003);国家自然科学基金青年基金(12105368)。

摘　　要：MR加速器具有软组织分辨率高、不需金标/信标置入的优势, 且可实现自适应靶区勾画和计划设计;完美解决前列腺放疗期间体积变化、每分次治疗时膀胱和直肠变化对靶区和剂量分布的影响等问题, 有望在靶区剂量安全前提下将外放边界继续缩小。但形状自适应流程临床执行难度较大, 本文将总结我科经验及标准操作流程。With aligned MR registration,the MR-Linac provides superior soft tissue resolution for prostate cancer.No fiducial markers or electromagnetic transponders insertion is needed to guarantee high-precision radiotherapy.The highly-recommended Adapt-To-Shape(ATS)workflow can resolve all the problems encountered during prostate cancer radiotherapy,including prostate volume changes and adjacent organs motion,both inter-fractionally and intra-fractionally.With all the above advantages,MR-Linac performs outstandingly than conventional linac in prostate cancer RT delivery,and probably helps us to reduce the CTV-PTV margin safely in the near future.Nevertheless,it is difficult to implement the ATS workflow in clinical practice.In this article,the standard ATS workflow for prostate cancer was summarized based on our own experience.

关 键 词：前列腺肿瘤 磁共振加速器 高精度 自适应放疗 流程 

分 类 号：R737.25[医药卫生—肿瘤]