阴茎转移性肿瘤5例报告并文献复习  

Metastatic tumor of penis:5 cases report and literatures review

作　　者：晏睿 梁丽 傅鑫华 包业炜 刘冰[1] 王林辉[4] 房晓[1] 王军凯[1] Yan Rui;Liang Li;Fu Xinhua;Bao Yewei;Liu Bing;Wang Linhui;Fang Xiao;Wang Junkai(Department of Urology,Changzheng Hospital,Naval Medical University(Second Military Medical University),Shanghai,200003,China;Department of Nuclear Medicine,Changhai Hospital,Naval Medical University(Second Military Medical University),Shanghai,200433,China;Department of Urology,Jing’an District Zhabei Central Hospital,Shanghai,200070,China;Department of Urology,Changhai Hospital,Naval Medical University(Second Military Medical University),Shanghai,200433,China)

机构地区：[1]海军军医大学(第二军医大学)长征医院泌尿外科,上海200003 [2]海军军医大学(第二军医大学)长海医院核医学科,上海200433 [3]上海市静安区闸北中心医院泌尿外科,上海200070 [4]海军军医大学(第二军医大学)长海医院泌尿外科,上海200433

出　　处：《中国男科学杂志》2021年第6期79-82,共4页Chinese Journal of Andrology

摘　　要：目的通过收集整理5例阴茎转移性肿瘤患者的临床资料并文献复习,提高对阴茎转移性肿瘤的认知。方法回顾整理2013年以来上海长征医院泌尿外科收治的5例阴茎转移性肿瘤患者的临床资料,结合国内外相关文献,讨论其临床特征、发病机理、诊疗措施及预后。结果5例阴茎转移性肿瘤患者平均诊断年龄为73.4岁,其中原发肿瘤来源膀胱癌2例,乙状结肠癌1例,恶性淋巴瘤1例,恶性黑色素瘤1例。3例患者表现为阴茎疼痛性结节,1例患者表现为无痛性黑色肿物,1例患者表现为阴茎肿大伴尿线变细。淋巴瘤患者发现时已出现阴茎转移,另外4例患者原发肿瘤确诊时间和阴茎转移性肿瘤确诊时间分别间隔39、58、3、8月。2例患者行阴茎部分切除术,3例患者行阴茎全切术明确诊断并缓解症状。除1例患者失访外,其余四例患者术后生存时间分别为9、6、27、7月。结论阴茎转移性肿瘤常见于盆腔脏器原发肿瘤经静脉或淋巴系统逆行转移,亦可见其他远处肿瘤转移,以阴茎单发性或多发性、疼痛性或无痛性结节为主要临床症状。阴茎转移性肿瘤的治疗主要取决于原发肿瘤情况及患者一般状况,阴茎部分切除术或全切术对缓解患者疼痛或尿路梗阻症状有益,但不能改变其预后较差的现实。Objective To improve the cognition of penile metastatic tumor by summarizing clinical data of 5 patients with penile metastatic tumor and reviewing the related literatures.Methods Clinical data of 5 patients with penile metastatic tumor treated in the Department of Urology of Shanghai Changzheng Hospital since 2013 were reviewed.Their clinical features,pathogenesis,treatment and prognosis were discussed combined with the relevant literature.Results The average age of 5 patients with penile metastatic tumor was 73.4 years.Among these 5 patients,2 cases of primary tumor originated from bladder cancer,1 case from sigmoid colon cancer,1 case from malignant lymphoma and 1 case from malignant melanoma.Three patients presented with painful nodule of penis,one patient with painless mass and one patient with enlarged penis and thinner urinary line.The patient with malignant lymphoma had penile metastasis at the time of diagnosis.The time interval between diagnosis of primary tumor and penile metastatic tumor in the other four patients was 39,58,3 and 8 months.Two patients underwent partial penile resection,and three patients underwent total penile resection to clear diagnosis and relieve clinical symptoms.One patient was lost to follow-up,and the survival time after surgery of the other four patients was9,6,27 and 7 months,respectively.Conclusion Penile metastatic tumors are common in primary pelvic tumors with retrograde metastasis through vein or lymphatic system,and the main clinical symptoms are solitary or multiple penile nodules,painful or painless nodules.The treatment of metastatic penile cancer mainly depends on the condition of the primary tumor and the general condition of the patient.Partial or total penile resection is beneficial to relieve pain or urinary tract obstruction,but it has no effect on poor prognosis.

关 键 词：阴茎肿瘤 肿瘤转移 膀胱肿瘤 直肠肿瘤 淋巴瘤 黑色素瘤 

分 类 号：R737.27[医药卫生—肿瘤] R737.14[医药卫生—临床医学]