癫痫发作后状态及其临床意义  

The postictal state in epilepsy and its clinical significance

作　　者：顾丽 余年[1] 狄晴[1] Gu Li;Yu Nian;Di Qing(Department of Neurology,the Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学附属脑科医院神经内科,南京210029

出　　处：《中华神经科杂志》2022年第1期65-70,共6页Chinese Journal of Neurology

摘　　要：癫痫发作后状态(PIS)是指癫痫发作停止到恢复至发病前水平的异常状态,包括认知、运动、感觉、自主神经和精神行为等异常,症状多样,严重程度不一,持续数秒至数天不等,对患者的健康和生活质量产生很大影响。然而,目前国内外相关的研究较少,临床医生对此缺乏正确认识,容易误诊误治。本文将从PIS的定义、病理生理机制、临床表现、诊断和鉴别诊断、临床意义以及干预策略等进行综述,以提高临床医生的认识,并为今后临床研究提供参考。The postictal state refers to the abnormal condition occurring between the end of an epileptic seizure and return to baseline condition,including a variety of cognitive,motor,sensory,autonomic,mental and behavioral impairments.The symptoms which may last from seconds to days are various and the severity is different.It also may exert great impact on patients′health and quality of life.However,the lack of relevant studies at home and abroad,along with the absence of correct understanding of this in clinical practice,may lead to frequent misdiagnosis and mistreatment.This article will review the concepts,pathophysiological mechanisms,clinical manifestations,diagnosis,differential diagnosis,clinical significance and intervention strategies,aiming at deepening the understanding of the phenomenon,as well as providing references for further clinical research.

关 键 词：癫痫 发作后状态 临床表现 鉴别诊断 定位 

分 类 号：R742.1[医药卫生—神经病学与精神病学]