下咽癌患者咽后淋巴结转移情况及临床特征分析  

Analysis of Retropharyngeal Lymph Node Metastasis and Clinical Characteristics in Patients with Hypopharyngeal Carcinoma

作　　者：黄昌群 高英[2] HUANG Chang-qun;GAO Ying(Department of Otolaryngology,Xi'an Fifth Hospital,Xi'an,Shaanxi 710082)

机构地区：[1]西安市第五医院耳鼻喉科,陕西西安710082 [2]延安大学附属医院鼻咽喉头颈外科,陕西延安716000

出　　处：《医学临床研究》2021年第12期1843-1845,共3页Journal of Clinical Research

摘　　要：【目的】探讨下咽癌患者咽后淋巴结转移情况及临床特征。【方法】回顾性分析本院收治的136例下咽癌患者的一般资料,TNM分期以及临床病灶分布的情况,根据患者咽后淋巴结转移情况将患者分为咽后淋巴结转移组和未转移组,比较两组患者的临床特征、术后区域复发情况以及生存率。【结果】136例下咽癌患者中,26例患者出现淋巴结转移(转移组),占比19.12%;110例患者未出现淋巴结转移(未转移组),占比80.88%;转移组与未转移组男性、年龄≥60岁、吸烟、术后化疗、高脂血症、糖尿病比例相比较差异均无显著性(P>0.05);转移组Ⅲ+Ⅳ期、中/高分化、有远处转移的患者占比均高于未转移组患者(P<0.05);Ⅲ+Ⅳ期、中/高分化、有远处转移均是影响患者淋巴结转移的危险因素(OR=2.052、3.536、3.881,均P<0.05)。【结论】在咽癌患者中,淋巴结转移率为19.12%,Ⅲ+Ⅳ期、中/高分化、有远处转移均是影响患者淋巴结转移的危险因素。【Objective】To investigate the retropharyngeal lymph node metastasis and its clinical characteristics in patients with hypopharyngeal carcinoma.【Methods】A total of 136 patients with hypopharyngeal cancer treated in our hospital were analyzed retrospectively.The TNM stage and clinical focus distribution of all patients with hypopharyngeal cancer were counted.According to the metastasis of retropharyngeal lymph nodes,the patients were divided into retropharyngeal lymph node positive group and retropharyngeal lymph node negative group.The clinical characteristics,postoperative regional recurrence and survival rate of the two groups were compared.【Results】Among 136 patients with hypopharyngeal carcinoma,26 patients had lymph node metastasis(the metastasis group),accounting for 19.12%;and 110 patients had no lymph node metastasis(non metastasis group),accounting for 80.88%.There was no significant difference between the metastatic group and the non metastatic group in men patients with age≥60,smoking,postoperative chemotherapy,hyperlipidemia and diabetes(P>0.05).The proportions of stageⅢ+Ⅳ,medium/high differentiation and distant metastasis in the metastasis group were higher than those in the non metastasis group(P<0.05).StageⅢ+Ⅳ,medium/high differentiation and distant metastasis were the risk factors of lymph node metastasis in the metastasis group(OR=2.052,3.536,3.881,P<0.05).【Conclusion】The rate of lymph node metastasis is 19.12%in patients with pharyngeal cancer.StageⅢ+Ⅳ,medium/high differentiation and distant metastasis are the risk factors of lymph node metastasis in the metastasis group.

关 键 词：下咽肿瘤 淋巴转移 预后 

分 类 号：R739.63[医药卫生—肿瘤]