氧化应激与牙周炎和糖尿病的关联性研究现状  

Current research on the relationship between oxidative stress, periodontitis and diabetes

作　　者：邓健文(综述) 陈珂晓(综述) 马淑媛(审校) 李泽键(审校)[1,2] DENG Jian-wen;CHEN Ke-xiao;MA Shu-yuan;LI Ze-jian(School of Stomatology,Jinan University,Guangzhou 510000,Guangdong,CHINA;Department of Stomatology,the First Affiliated Hospital of Jinan University,Guangzhou 510000,Guangdong,CHINA)

机构地区：[1]暨南大学口腔医学院,广东广州510000 [2]暨南大学附属第一医院口腔科,广东广州510000

出　　处：《海南医学》2022年第2期250-253,共4页Hainan Medical Journal

基　　金：国家自然科学基金(编号:81804153);广东省自然科学基金(编号:2019A15110161);广东省中医药局科研项目(编号:20191090/20201107);中央高校科研项目(编号:21619344)。

摘　　要：牙周炎是最常见的口腔疾病之一,其已被确定为糖尿病患者代谢控制不良的一个可能危险因素。牙周炎症或糖尿病的代谢异常会促进活性氧的大量形成,导致口腔内发生氧化应激。越来越多证据表明,氧化应激是促进牙周炎、糖尿病进展的重要因素。本文对氧化应激与糖尿病和牙周炎的关联性做一综述。Periodontitis is one of the most common oral diseases, and it has been identified as a possible risk factor for poor metabolic control in diabetic patients. Periodontal inflammation or abnormal metabolism of diabetes will promote the formation of a large amount of reactive oxygen species, leading to oxidative stress in the oral cavity. More and more evidence show that oxidative stress is an important factor in promoting the progression of periodontitis and diabetes. This article reviews the relationship between oxidative stress, diabetes and periodontitis.

关 键 词：氧化应激 牙周炎 糖尿病 活性氧 丙二醛 8-羟化脱氧鸟苷 羰基蛋白 氧化损伤 

分 类 号：R781.4[医药卫生—口腔医学]