心血管疾病住院患者营养风险与抑郁状态的关系  

Relationship between Nutritional Risk and Depression in Hospitalized Patients with Cardiovascular Diseases

作　　者：万姜 李琦[1] 杨杰 袁润 王楚耘 陈纪春[1] 李响[1] WAN Jiang;LI Qi;YANG Jie;YUAN Run;WANG Chu-yun;CHEN Ji-chun;LI Xiang(Department of Nutrition,Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China)

机构地区：[1]中国医学科学院,北京协和医学院,阜外医院营养科,北京市100037

出　　处：《中国分子心脏病学杂志》2021年第6期4296-4299,共4页Molecular Cardiology of China

基　　金：“十三五”国家重点研发计划(2017YFC0211702);中国医学科学院医学与健康科技创新工程(2016-I2M-3-018)。

摘　　要：目的探讨心血管疾病住院患者存在的营养风险与抑郁状态的关系。方法选择2021年9~10月住院治疗的心血管病患者201例。应用营养风险筛查量表(NRS2002)进行营养风险评估,同时采用Zung抑郁自评量表评估抑郁状态。比较抑郁组与无抑郁组患者基本特征差异,以多因素logistic回归模型分析营养风险与抑郁状态的关系。结果201例患者中,存在营养风险者93例(46.3%),处于抑郁状态者125例(62.2%)。抑郁组患者年龄、合并冠状动脉粥样硬化性心脏病、糖尿病、接受手术以及营养风险评分≥4分者的比例均高于无抑郁组患者,且差异均有统计学意义(P<0.05)。多因素logistic回归分析结果显示,年龄≥50岁者(OR=2.172)、接受手术治疗者(OR=2.603)出现抑郁状态的风险增高(P<0.05);以NRS2002评分1分为对照,4分和5~6分者的抑郁风险OR(95%CI)值分别达到5.234(1.545-17.735)和11.464(2.528-51.980)。结论心血管疾病住院患者高营养风险与抑郁状态正相关,及时开展营养风险筛查及营养干预将有助于缓解和减少抑郁的发生。Objective To investigate the association between nutritional risk and depression of patients with cardiovascular diseases(CVD)in hospital.Methods A cross-sectional study was conducted on CVD patients hospitalized from September to October 2021.Participants who met the criteria received assessments by nutrition risk screening scale(NRS2002)and the Zung self-rating depression scale.The differences between the inpatients with and without depression were compared.The relationship between nutritional risk and depression status was analyzed by multivariate logistic regression.Results Among the 201 participants,93(46.3%)were at nutritional risk and 125(62.2%)were depressed.In univariate analysis,the average age,the proportion of patients with coronary heart disease,diabetes,surgery and nutritional risk score≥4 in the depressed group were higher than those in the non-depressed group.The differences were statistically significant(P<0.05).Multivariate regression analysis showed that the OR(95%CI)of depression was 5.234(1.545-17.735)and 11.464(2.528-51.980)in patients with 4 and 5-6 points,respectively,compared with those having NRS2002 score of 1.In addition,age≥50 years old(OR=2.172)and surgical treatment(OR=2.603)increased the risk of depression(P<0.05).Conclusion High nutritional risk in hospitalized patients with cardiovascular diseases is positively correlated with depression.Therefore,timely nutritional risk screening and nutritional intervention will help alleviate and reduce depression.

关 键 词：心血管疾病 住院患者 营养风险 抑郁 

分 类 号：R749.4[医药卫生—神经病学与精神病学]