光学离焦技术控制近视的研究进展  

Slowing the progression of myopia with the optical defocus strategies

作　　者：陈楠[1] 薛劲松[1] 蔡江怀 蒋沁[1] 陈凯[1] 颜智鹏[1] 许薇 李新华[2,3] 杨卫华 Nan Chen;Jin-Song Xue;Jiang-Huai Cai;Qin Jiang;Kai Chen;Zhi-Peng Yan;Wei Xu;Xin-Hua Li;Wei-Hua Yang(The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China;School of Materials Science & Engineering, Jinling Institute of Technology, Nanjing 211169, Jiangsu Province, China;Nanjing Key Laboratory of Optometric Materials and Technology, Nanjing 211169, Jiangsu Province, China)

机构地区：[1]南京医科大学附属眼科医院,中国江苏省南京市210029 [2]金陵科技学院材料工程学院,中国江苏省南京市211169 [3]中国江苏省南京市视光材料与技术重点实验室,211169

出　　处：《国际眼科杂志》2022年第2期260-264,共5页International Eye Science

摘　　要：近视是一种常见的眼病,近年来,近视的发生率在全球范围内呈逐年上升趋势,高度近视会增加视力丧失的风险,近视的并发症可引起巨大的经济和社会效益损失。因此,实施控制近视的有效措施至关重要且迫在眉睫。人们对近视的发病机制研究表明,周围远视离焦引起眼球轴向伸长不受控制可能是近视发展的机制之一,由此引申的各种光学策略尤其是光学离焦技术控制近视日益成为近视管理主流临床实践的一部分。本文从光学离焦控制近视的原理、离焦性近视动物实验研究、不同光学离焦技术控制近视的最新临床应用等方面进行综述,总结了使用渐进多焦眼镜、周边离焦框架眼镜、多点近视离焦框架眼镜、角膜塑形镜及多焦点软性角膜接触镜控制近视的临床研究结果,拟为延缓近视进展的治疗方案设计提供新的选择。Myopia is a common ocular disorder.In recent years,the incidence of myopia presents an increasing trend year by year.Patients with high myopia are at an increased risk for severe visual impairment.The economic and societal impacts of complication associated with myopia are enormous.Therefore,it is essential and imminent for implementing effective myopia control strategies.The results of the current study suggest that uncontrolled axial elongation produced by periphral hyperopic defocus could be one of the possible mechanisms for myopia development,multiple strategies especially optical defocus technology based on this are increasingly becoming part of the mainstream clinical practice in myopia management.This article reviews the principle of optical defocus on myopia control,experimental research on defocus myopia animals,and the latest clinical applications of different optical defocus technologies on myopia control,summarizes the clinical research results of myopia control using progressive addition spectacle lenses,peripheral defocus spectacle lenses,defocus incorporated multiple segments spectacle lenses,orthokeratology contact lenses and multifocal soft contact lenses.It is proposed to provide a new option for the treatment plan to delay the progression of myopia.

关 键 词：近视 光学离焦 框架眼镜 角膜接触镜 控制近视 

分 类 号：G63[文化科学—教育学]