经皮微创球囊压迫术治疗难治性三叉神经痛的疗效  

Efficacy of percutaneous microballoon compression for the treatment of patients with intractable trigeminal neuralgia

作　　者：王礼彬 胡琴琴 舒亮晶 胡柳生 李宜红 严雄 童赟 Wang Libin;Hu Qinqin;Shu Liangjing;Hu Liusheng;Li Yihong;Yan Xiong;Tong Yun(Department of Painology,Affiliated Hospital of Jiujiang College,Jiujiang City,Jiangxi Province 332000,China;Department of Psycology,the Fifth People's Hospitalof Jiujiang City,Jiujiang City,Jiangxi Province 332000,China)

机构地区：[1]九江学院附属医院疼痛科,江西省九江市332000 [2]九江市第五人民医院心理科,江西省九江市332000

出　　处：《中华疼痛学杂志》2021年第6期608-613,共6页Chinese Journal Of Painology

基　　金：江西省卫生健康委科技计划(20205008)。

摘　　要：目的探讨经皮微创球囊压迫术(PMC)治疗难治性三叉神经痛的临床效果。方法回顾性分析2017年6月至2020年2月在九江学院附属医院疼痛科住院的原发性难治性三叉神经痛患者65例,其中男26例,女39例,年龄46~84岁,所有患者均在全身麻醉下行经皮微创球囊压迫术。采用视觉模拟评分(VAS)对术前,术后1 d,1周、1、3、6个月和1年时疼痛程度进行评分,应用改良MacNab标准进行疗效评价。结果与术前比较,患者术后1 d、1周、1、3、6、12个月时VAS评分均降低,差异均有统计学意义(P均<0.05),VAS评分0~3分患者例数均增加,差异均有统计学意义(P均<0.05)。术后1 d、1周,1、3、6、12个月时,优良率分别为87.7%(57/65例)、92.8%(61/65例)、96.9%(63/65例)、98.5%(64/65例)、98.5%(64/65例)和96.9%(63/65例),与术后1 d比较,其他评价时点优良率均较高,差异有统计学意义(P均<0.05)。所有患者均未见严重并发症。结论经皮微创球囊压迫术治疗难治性三叉神经痛安全有效。Objective To explore the efficacy of percutaneous microballoon compression technique for the treatment of patients with intractable trigeminal neuralgia.Methods Sixty-five patients with primary intractable trigeminal neuralgia,26 male and 39 female,aged 46-84 years old,in the Department of Painology,Affiliated Hospital of Jiujiang College,were retrospectively collected from June 2017 to February 2020.All patients underwent percutaneous microballoon compression under general anesthesia.The visual analogue scale and MacNab curative effect were recorded before and after the treatment at 1 day,1 week,1 month,3 months,6 months and 1 year.Results Compared with pretreatment,VAS decreased at 1 d,1 week,1,3,6 and 12 months after the treatment(all P<0.05),and the number of VAS 0-3 increased(all P<0.05).The excellent and good rate was 87.7%(57/65 cases),92.8%(61/65 cases),96.9%(63/65 cases),98.5%(64/65 cases),98.5%(64/65 cases),and 96.9%(63/65 cases)at 1 day,1 week,1,3,6 and 12 months after the treatment respectively,and all higher than that before the treatment(all P<0.05).No patients reported serious complications.Conclusion Percutaneous microballoon compression technique is a safe and effective method in the treatment of patient with intractable trigeminal neuralgia.

关 键 词：三叉神经痛 疼痛 顽固性 球囊压迫术 疗效 

分 类 号：R745.11[医药卫生—神经病学与精神病学]