High Risk of Malnutrition in Uyghur Patients with Cancer in China  

作　　者：Xiao Ru Jiang Chun Hua Song Hong Xia Xu Jiu Wei Cui Yuan Lin Jun Qiang Chen Qing Chuan Zhao Zeng Qing Guo Kun Hua Wang Ying He Su Yi Li Hu Ma Han Ping Shi Jing Wu 无 

机构地区：[1]Department of Epidemiology and Statistics,College of Public Health,Zhengzhou University,Zhengzhou 450001,Henan,China [2]Third Military Medical University(Army Medical University),Chongqing 400042,China [3]Cancer Center of the First Hospital of Jilin University,Changchun 130021,Jilin,China [4]Department of Gastrointestinal Surgery,Affiliated Tumor Hospital of Guangxi Medical University,Nanning 530021,Guangxi,China [5]Department of Gastrointestinal Surgery,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi,China [6]Department of Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,Shaanxi,China [7]Department of Medical Oncology,Fujian Cancer Hospital,Fujian Medical University Cancer Hospital,Fuzhou 350014,Fujian,China [8]Department of Gastrointestinal Surgery,Institute of Gastroenterology,The First Affiliated Hospital of Kunming Medical University,Kunming 650032,Yunnan,China [9]Department of Clinical Nutrition,Chongqing General Hospital,Chongqing 400014,China [10]Department of Nutrition and Metabolism of Oncology,Affiliated Provincial Hospital of Anhui Medical University,Hefei 230031,Anhui,China [11]Department of Oncology,Affiliated Hospital of Zunyi Medical University,Zunyi 563000,Guizhou,China [12]Department of Gastrointestinal Surgery/Clinical Nutrition,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China [13]Department of Clinical Nutrition,The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Traditional Chinese Medicine),Hangzhou 310006,Zhejiang,China. [14]The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group,Chinese Society of Nutritional Oncology

出　　处：《Journal of Nutritional Oncology》2021年第4期176-185,共10页肿瘤营养学杂志（英文）

基　　金：supported by Henan University Science and Technology Innovation Talents Support Program(19HASTIT005);the National Key Research and Development Program(No.2017YFC1309200);the Medical Science and Technology Key Projects of Henan Province and Zhengzhou(192102310088,19A32000820).

摘　　要：Background Patients with advanced cancer often present with malnutrition.Globally,minority populations frequently suffer from higher rates of malnutrition than the majority group.It was unknown whether the nutritional status of cancer patients is different between ethicality groups(i.e.Uyghur and Han)in China.Methods A total of 251 Uyghur cancer patients were enrolled from the Xinjiang Kashgar First People's Hospital in the INSCOC Program.The Han patients were 1∶1 matched to Uyghur patients by age,gender and type of cancer from 72 hospitals around China in INSCOC Program.The nutritional risk and nutritional status were assessed using the Nutrition Risk Screening 2002(NRS 2002)and Patient-Generated Subjective Global Assessment(PG-SGA),respectively.Then,the functional status of cancer patients was determined based on the Karnofsky Performance Status(KPS).Results The incidence of an abnormal NRS-2002(≥3),PG-SGA(≥4),and KPS(≤70)was significantly different(86.1%vs 59.0%,70.5%vs 27.5%,and 18.7%vs 4.0%,respectively P<0.05).The abnormal rate of laboratory indicators in Uyghur cancer patients was significantly higher than that in Han cancer patients,including total protein,albumin,serum total bilirubin,direct bilirubin,HDL-C,white blood cell,lymphocyte,red blood cell,and platelet(all P<0.05).The abnormal rates of TSF,HGS and CC were significantly higher than that of Han nationality patients(17.5%vs 9.7%,39.6%vs 19.6%,29.1%vs 15.2%,P<0.001).The nutritional support rate of Uyghur patients was lower than that of Han patients(0%vs 16.3%).After adjusting for potential risk factors,malnutrition was associated with gender(female,OR=0.35,95%CI=0.13-0.92,P=0.034),age(>60 years,OR=5.32,95%CI=1.46-19.41,P=0.011),cancer type(gastroesophageal tumor,OR=33.62,95%CI=3.42-330.67,P=0.003),and treatment methods(received radical tumor resection,OR=5.78,95%CI=1.45-23.08,P=0.008;received radiotherapy or chemotherapy:OR=7.69,95%CI=2.27-26.04,P<0.001).Conclusions The nutritional status of Uyghur cancer patients is worse than that of Han

关 键 词：MALNUTRITION NRS-2002 Nutritional assessment Nutritional status PG-SGA Uyghur cancer patients 

分 类 号：R730.6[医药卫生—肿瘤]